Effect of foot and mouth disease on haematological and biochemical profile of cattle

Barkakati, Juri; Sarma, S.; Kalita, Dhruba Jyoti

doi:10.18805/ijar.5588

Cited by 8 publications

(8 citation statements)

References 6 publications

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“…These findings coinside with other reports indicating the predominance of serotype O [10,21,22]. In infected cows there were no significant changes in RBCs, Hb, PCV, MCV, MCH and MCHC in comparison with apparently healthy ones [23], this might be due to the absence of hemorrhage and hemolysis in cows with FMD infection [24]. In infected buffaloes, there was a decrease in the level of RBCs than the control group which could be attributed to a reduction of the process of erythropoesis [24].…”

Section: Discussionsupporting

confidence: 82%

“…In infected cows there were no significant changes in RBCs, Hb, PCV, MCV, MCH and MCHC in comparison with apparently healthy ones [23], this might be due to the absence of hemorrhage and hemolysis in cows with FMD infection [24]. In infected buffaloes, there was a decrease in the level of RBCs than the control group which could be attributed to a reduction of the process of erythropoesis [24]. The normocytic normochromic anemia could be resulted from endocrinopathy occurring secondary to viral infection [25] or due to decreased feed intake as a consequence of mouth ulceration.…”

Section: Discussionmentioning

confidence: 77%

“…The disease leads also to economic losses which include reduction in milk and meat production, reproductive inefficiencies and death in young ruminants [1]. It is characterized clinically by fever, depression, anorexi and, excessive foamy salivation with vesicles appearing on the tongue [2]. Some infected animals remain asymptomatic, but they dissiminate the virus to other animals.…”

Section: Introductionmentioning

confidence: 99%

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Molecular Characterization, Hematological and Biochemical Studies on Foot and Mouth Disease Virus Serotype O in Buffaloes and Cows in Dakahlia Governorate, Egypt

El-Mandrawy

Farag

2017

Zagazig Veterinary Journal

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The present study aimed to evaluate the hematological and serum biochemical parameters in buffaloes and cows infected with foot and mouth disease (FMD) virus. Forty buffaloes and cows (6 months-2 years old) were used. Twenty buffaloes and cows clinically healthy and were used as control, the other twenty buffaloes and cows showed characteristic clinical signs of FMD. Blood samples were collected and serum was separated from both groups to measure the hematological and biochemical parameters. Infected buffaloes and cows showed fever, anroxia, excessive foamy salivation and ulcer formation in the mouth. Compared to the control buffaloes, erythrocytic count (RBCs), hemoglobin (Hb) and packed cell volume (PCV) in the FMD infected buffaloes were significantly decreased, while mean corpascular hemoglobin (MCH) was significantly increased. In addition, significant increase in toltal leukocyte count (TLC), neutrophils, with a significant decrease in eosinophil and lymphocyte counts were observed. Moreover, cows infected with FMD virus showed no significant changes in the erythrogram, while, significant increases in TLC and neutrophils, with a significant decrease in eosinophil and lymphocyte counts were observed when compared with the control group. There were significant decreases in the levels of serum total proteins, albumin and globulin, while serum asprtate transferase (AST), creatinine phospho-kinase (CPK), glucose and cortisol levels were significantly increased in the infected animals. Tissue and saliva specimens were collected and analyzed by using universal primer using reverse-transcription polymerase chain reaction (RT-PCR). All the identified viruses were of serotype 'O'. It is concluded that FMDV serotype 'O' is circulating among cows and buffaloes in the study area.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 77%

Section: Introductionmentioning

confidence: 99%

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Molecular Characterization, Hematological and Biochemical Studies on Foot and Mouth Disease Virus Serotype O in Buffaloes and Cows in Dakahlia Governorate, Egypt

El-Mandrawy

Farag

2017

Zagazig Veterinary Journal

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“…The serotypes of FMDV recorded in Egypt are SAT2, A and O [4]. The disease is characterized by fever, anorexia and excessive foamy salivation with vesicles appearing on tongue, gums, cheeks, pharynx and hard palate [5,6]. Lameness is evident in animals with foot lesions.…”

Section: Introductionmentioning

confidence: 99%

Molecular Diagnosis of Foot and Mouth Disease Virus in Cattle with Reference to Hematological and Biochemical Changes

Hashem

El-Mandrawy

Araby

et al. 2018

Zagazig Veterinary Journal

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The present study was carried out to clarify the effect of Foot and Mouth Disease Virus (FMDV) on cattle of different ages with references to studying the hematological parameters, biochemical aspects and cardiac biomarkers after accurate diagnosis of FMDV by reverse transcriptionpolymerase chain reaction (RT-PCR). Forty-five native breed Egyptian female non pregnant cattle (1-5 years old) were divided into two main groups. Group (1): 15 apparently healthy cattle as control group. This group includes animals at age 1-1.5 year (gp.1a), 2-3 years (gp.1b) and 4-5 years (gp.1c). Group (2): 30 infected cattle with the same age category as the control group (gp. 2a, gp. 2b and gp.2c) were collected from different localities in port-Said Governorate, Egypt during 2016-2017 FMD outbreak. Saliva and vesicular fluid from infected cattle were obtained for RT-PCR and blood samples for hematological and biochemical parameters estimation. The infected cattle showed fever, ropy salivation, vesicular eruptions on buccal mucosa and interdigital space. All the identified viruses were FMDV of serotype 'O' which is circulating among cows of different ages in Egypt. Biochemical results revealed a significant decrease in serum total proteins, albumin, globulins and calcium levels, with a significant increase in serum enzyme activities ALP, GGT, AST and serum levels of urea, creatinine, inorganic phosphrous, malonadiadehyde, nitric oxide, Interleukein10 (IL-10), cardiac tropinine I (cTn I) and creatine kinase MB (CK-MB) concentration. It was concluded that FMDV significantly affects the hematological and biochemical parameters of infected cattle, especially young one. The detection of cTnI is a very sensitive method for determining myocardial cell damage in the earlier stages of the disease. Moreover, RT-PCR is diagnostic biomarkers for FMD viral infection.

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“…The epidemiology and etiology of FMD have been extensively investigated [2]. However, there are few published reports on the changes of the hemato-biochemical parameters in cattle and pigs after FMD vaccination.…”

mentioning

confidence: 99%

Blood parameter changes in Korean traditional calves and pigs after foot-and-mouth disease vaccination

Cha¹,

Park²,

Yoo³

et al. 2017

Korean Journal of Veterinary Research

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This study investigated changes in certain blood parameters in calves and pigs after foot-and-mouth disease (FMD) vaccination. In this study, five calves and five pigs were selected from groups of 10 calves and pigs, respectively, and were vaccinated with an FMD vaccine. The remaining animals formed two non-treatment control groups. Blood samples were collected from all animals on the 1st, 3rd, 5th, and 7th days post-vaccination. In the FMD-vaccinated calves and pigs on day 7 post-vaccination, white blood cell counts, blood urea nitrogen levels, and alanine aminotransferase and aspartate aminotransferase activities were higher than those in the respective controls. The present data suggested that the certain hemato-biochemical parameters on cattle and pigs were meaningfully changed between before and after FMD vaccination.

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Effect of foot and mouth disease on haematological and biochemical profile of cattle

Cited by 8 publications

References 6 publications

Molecular Characterization, Hematological and Biochemical Studies on Foot and Mouth Disease Virus Serotype O in Buffaloes and Cows in Dakahlia Governorate, Egypt

Molecular Characterization, Hematological and Biochemical Studies on Foot and Mouth Disease Virus Serotype O in Buffaloes and Cows in Dakahlia Governorate, Egypt

Molecular Diagnosis of Foot and Mouth Disease Virus in Cattle with Reference to Hematological and Biochemical Changes

Blood parameter changes in Korean traditional calves and pigs after foot-and-mouth disease vaccination

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