Present study was undertaken to know certain haematological and serum profile in FMD affected and recovered cattle. The RBC count in FMD affected, recovered and apparently healthy group were 5.18±0.11, 5.50±0.13 and 5.68±0.10X106 /µl respectively. The RBC count was found to be decreased significantly (P<0.05) in affected animals than the apparently healthy group. The WBC count, haemoglobin and PCV in FMD affected, recovered and apparently healthy animals did not differ significantly. Serum protein (P<0.01), albumin (P<0.05) and blood urea nitrogen (P<0.01) significantly decreased in FMD affected animals. Blood glucose concentration in FMD affected group (47.58±2.28 mg/dl) showed a significant (P< 0.01) increase as compared to recovered (40.43±1.73 mg/dl) and apparently healthy group (39.63±1.68 mg/dl). The serum calcium was significantly (P< 0.01) decreased in the FMD affected group (7.67±0.10 mg/dl). From this study, it can be concluded that, FMD causes significant decrease of RBC count, total protein, albumin, BUN, calcium and significant increase of glucose.

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Present study was undertaken to elucidate the effect of Foot and Mouth Disease on the activity of different serum enzymes and hormone profile in indigenous cattle of Assam. The serum alkaline phosphatase (ALP) and alanine transaminase (ALT) activity did not show significant difference among the affected, recovered and control group. However, significant (P is less than 0.01) increase of aspartate transaminase (AST) activity was recorded in the affected group as compared to control. The level of T3 showed a significant (Pis less than 0.05) increase during FMD infection. T4 and cortisol hormones were also found to be increased significantly (Pis less than 0.01) in FMD affected than recovered and control group. From the present study, it can be concluded that during FMD, there is a significant increase of AST , T3, T4 and cortisol. However, no significant change was recorded in the activity of ALT and ALP during FMD infection and recovered group..