Effect of Fucus evanescens Fucoidan on Expression of Matrix Metalloproteinase-1 Promoter, mRNA, Protein and Signal Pathway

Ku, Mi Jeong; Jung, Ji Won; Lee, Myeong Sook; Cho, Byung Kyu; Lee, Soon Rye; Lee, Hye-Sook; Vischuk, Olesya S.; Zvyagintseva, T. N.; Ermakova, Svetlana P.; Lee, Yong Hwan

doi:10.5352/jls.2010.20.11.1603

Cited by 8 publications

(7 citation statements)

References 30 publications

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“…Other less documented benefits described for Fucus spp. fucoidans include anti-obesity [ 92 ], anti-photoaging [ 127 , 128 ] and antibacterial [ 129 , 130 ].…”

Section: Nutrient Composition Of Fucus Sppmentioning

confidence: 99%

Phycochemical Constituents and Biological Activities of Fucus spp.

2018

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Seaweeds are known to be a good supply of key nutrients including carbohydrates, protein, minerals, polyunsaturated lipids, as well as several other health-promoting compounds capable of acting on a wide spectrum of disorders and/or diseases. While these marine macroalgae are deeply rooted in the East Asian culture and dietary habits, their major application in Western countries has been in the phycocolloid industry. This scenario has however been gradually changing, since seaweed consumption is becoming more common worldwide. Among the numerous edible seaweeds, members of the genus Fucus have a high nutritional value and are considered good sources of dietary fibers and minerals, especially iodine. Additionally, their wealth of bioactive compounds such as fucoidan, phlorotannins, fucoxanthin and others make them strong candidates for multiple therapeutic applications (e.g., antioxidant, anti-inflammatory, anti-tumor, anti-obesity, anti-coagulant, anti-diabetes and others). This review presents an overview of the nutritional and phytochemical composition of Fucus spp., and their claimed biological activities, as well as the beneficial effects associated to their consumption. Furthermore, the use of Fucus seaweeds and/or their components as functional ingredients for formulation of novel and enhanced foods is also discussed.

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“…Other less documented benefits described for Fucus spp. fucoidans include anti-obesity [ 92 ], anti-photoaging [ 127 , 128 ] and antibacterial [ 129 , 130 ].…”

Section: Nutrient Composition Of Fucus Sppmentioning

confidence: 99%

Phycochemical Constituents and Biological Activities of Fucus spp.

2018

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“…Previous studies have reported that fucoidan isolated from S. japonica has a variety of bioactivities, such as neuroprotective, anti-inflammation, antioxidant, antiviral, immunomodulatory, atherosclerosis mitigation and anticoagulant activities [16][17][18][19][20][21]. Some researchers have investigated the anti-UVB ability of fucoidan from brown seaweed, such as Costaria costata, Fucus evanescens and Undaria pinnatifida [22][23][24]; however, this is the first study on the anti-UVB activities of fucoidan extracted from S. japonica.…”

Section: Introductionmentioning

confidence: 98%

Protective Effect of a Fucose-Rich Fucoidan Isolated from Saccharina japonica against Ultraviolet B-Induced Photodamage In Vitro in Human Keratinocytes and In Vivo in Zebrafish

Wang

et al. 2020

Marine Drugs

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A fucose-rich fucoidan was purified from brown seaweed Saccharina japonica, of which the UVB protective effect was investigated in vitro in keratinocytes of HaCaT cells and in vivo in zebrafish. The intracellular reactive oxygen species levels and the viability of UVB-irradiated HaCaT cells were determined. The results indicate that the purified fucoidan significantly reduced the intracellular reactive oxygen species levels and improved the viability of UVB-irradiated HaCaT cells. Furthermore, the purified fucoidan remarkably decreased the apoptosis by regulating the expressions of Bax/Bcl-xL and cleaved caspase-3 in UVB-irradiated HaCaT cells in a dose-dependent manner. In addition, the in vivo UV protective effect of the purified fucoidan was investigated using a zebrafish model. It significantly reduced the intracellular reactive oxygen species level, the cell death, the NO production, and the lipid peroxidation in UVB-irradiated zebrafish in a dose-dependent manner. These results suggest that purified fucoidan has a great potential to be developed as a natural anti-UVB agent applied in the cosmetic industry.

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“…The photoprotective activity of fucoidan has been studied using UVB irradiated HaCaT and human foreskin fibroblast (HS 68) cells, zebrafish, and in vivo models [ 19 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 ]. The earliest study on the photoprotective activity of fucoidan was carried out by Kim et al in 2008.…”

Section: Seaweed Compounds As Potential Sources Of Anti-photoagingmentioning

confidence: 99%

“…The number, extraction, purification, and characterization of anti-photoaging compounds from marine sources are high and competitive compared to other marine floras such as sea grass, mangroves, and marine faunas (i.e., teripang or sea cucumber, sea star, sea urchin, and more). Furthermore, seaweed polysaccharides including fucoidan, laminarin, and carrageenan ( Figure 1 ) showed potential anti-photoaging properties which were mediated by intra-cellular ROS scavenging activity in UV irradiated cells and in vivo models [ 16 , 17 , 18 , 19 ]. Other seaweed-derived materials such as mycosporine like amino acids (MAAs) are well known as the most potential natural UVA-absorbing molecules [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Anti-Photoaging and Potential Skin Health Benefits of Seaweeds

2021

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The skin health benefits of seaweeds have been known since time immemorial. They are known as potential renewable sources of bioactive metabolites that have unique structural and functional features compared to their terrestrial counterparts. In addition, to the consciousness of green, eco-friendly, and natural skincare and cosmetics products, their extracts and bioactive compounds such as fucoidan, laminarin, carrageenan, fucoxanthin, and mycosporine like amino acids (MAAs) have proven useful in the skincare and cosmetic industries. These bioactive compounds have shown potential anti-photoaging properties. Furthermore, some of these bioactive compounds have been clinically tested and currently available in the market. In this contribution, the recent studies on anti-photoaging properties of extracts and bioactive compounds derived from seaweeds were described and discussed.

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Effect of Fucus evanescens Fucoidan on Expression of Matrix Metalloproteinase-1 Promoter, mRNA, Protein and Signal Pathway

Cited by 8 publications

References 30 publications

Phycochemical Constituents and Biological Activities of Fucus spp.

Phycochemical Constituents and Biological Activities of Fucus spp.

Protective Effect of a Fucose-Rich Fucoidan Isolated from Saccharina japonica against Ultraviolet B-Induced Photodamage In Vitro in Human Keratinocytes and In Vivo in Zebrafish

Anti-Photoaging and Potential Skin Health Benefits of Seaweeds

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