Effect of incorporating antifungals on the water sorption and solubility of interim resilient liners for denture base relining

Surface Properties of Temporary Soft Liners Modified by Minimum Inhibitory Concentrations of Antifungals

“…In the present study, chlorhexidine diacetate resulted in no harmful changes for the Shore A hardness of both temporary liners and the roughness of Trusoft. As the temporary soft lining materials are used for short periods, it has been suggested that small changes in physical and mechanical properties (as observed for the roughness of Softone modified with chlorhexidine) do not contraindicate their modification by antifungal agents (9,12,16). This protocol is important for improving the health of the soft tissues prior to the fabrication of new dentures.…”

“…A recent study demonstrated that after 14 days of water immersion, the addition of nystatin did not affect water sorption of two temporary soft lining materials (16). Despite these promising results, the authors identified no information in the literature regarding the effects of drug addition at MICs on other important properties of temporary soft lining materials.…”

Sustained drug-delivery system: a promising therapy for denture stomatitis?

“…With the exception of itraconazole, the MICs of drugs incorporated into temporary soft lining materials resulted in minimal changes in their peel bond strength to a denture base resin within 14 days 19 . After 14 days, the MICs of nystatin and ketoconazole in both materials and chlorhexidine in temporary resilient liner did not significantly influence their water sorption 10 . The solubility of both resilient materials was not modified by nystatin at MIC within 14 days 10 .…”

“…After 14 days, the MICs of nystatin and ketoconazole in both materials and chlorhexidine in temporary resilient liner did not significantly influence their water sorption 10 . The solubility of both resilient materials was not modified by nystatin at MIC within 14 days 10 . Also, in this issue, Lima, et al 11 observed that the addition of drugs at MICs resulted in no harmful effects for the porosity of both soft lining materials in different periods of water immersion, except for chlorhexidine and nystatin in the tissue conditioner and chlorhexidine in the temporary resilient liner at 14 days.…”

In situ evaluation of surface roughness and micromorphology of temporary soft denture liner materials at different time intervals

“…This could explain the lower roughness values found for Mucopren, in comparison with Trusoft.Moreover, the Trusoft temporary resilient liner contains plasticisers and ethyl alcohol that give it a lifespan of about 14 days 23. According to the manufacturer, the low concentration of plasticisers in Trusoft means that this material may be used clinically for up to 30 days.…”