Effect of Intravenous Atrial Natriuretic Peptide on Pulmonary Dysfunction and Renal Function Following Burn Shock

Abstract

Intravenous hANP seems to be effective for postresuscitative pulmonary dysfunction and renal function after burn shock in the vulnerable elderly, or patients with preexisting disease, suggesting that it could be valuable in facilitating fluid management in the acute phase in severely burned patients.

Ideal target arterial pressure after control of bleeding in a rabbit model of severe traumatic hemorrhagic shock: results from volume loading-based fluid resuscitation

“…These can contribute to vascular dysfunction, resulting in increased fluid requirement, laying rabbits at high risk for death. Treatment with human ANP has shown some benefits in patients with acute heart failure and burn shock [28,29]. Our study was the first to observe the value of ANP in THS.…”