Effect of Light at Night on oxidative stress markers in Golden spiny mice (Acomys russatus) liver

Ashkenazi, Lilach; Haim, Abraham

doi:10.1016/j.cbpa.2013.04.013

Cited by 9 publications

(6 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Light at night is also known to have deleterious consequences at the cellular level, affecting important mechanisms of cellular defense and redox homeostasis. Nocturnal melatonin increases antioxidant activity and attenuates a stress response in order to restore equilibrium (Ashkenazi & Haim, 2013). Consequently, exposure to short-wavelength artificial light can lead to serious health consequences, including increased oxidative stress with the potential for oxidative damage through peroxidation of membranes, fatty acids, and carbonylation of proteins (Ghiselli et al, 2000;Navara & Nelson, 2007;Schneeberger & Czirják, 2013).…”

Section: Discussionmentioning

confidence: 99%

Artificial light pollution: Shifting spectral wavelengths to mitigate physiological and health consequences in a nocturnal marsupial mammal

Dimovski

Robert

2018

J Exp Zool Pt A

View full text Add to dashboard Cite

The focus of sustainable lighting tends to be on reduced CO emissions and cost savings, but not on the wider environmental effects. Ironically, the introduction of energy-efficient lighting, such as light emitting diodes (LEDs), may be having a great impact on the health of wildlife. These white LEDs are generated with a high content of short-wavelength 'blue' light. While light of any kind can suppress melatonin and the physiological processes it regulates, these short wavelengths are potent suppressors of melatonin. Here, we manipulated the spectral composition of LED lights and tested their capacity to mitigate the physiological and health consequences associated with their use. We experimentally investigated the impact of white LEDs (peak wavelength 448 nm; mean irradiance 2.87 W/m ), long-wavelength shifted amber LEDs (peak wavelength 605 nm; mean irradiance 2.00 W/m ), and no lighting (irradiance from sky glow < 0.37 × 10 W/m ), on melatonin production, lipid peroxidation, and circulating antioxidant capacity in the tammar wallaby (Macropus eugenii). Night-time melatonin and oxidative status were determined at baseline and again following 10 weeks exposure to light treatments. White LED exposed wallabies had significantly suppressed nocturnal melatonin compared to no light and amber LED exposed wallabies, while there was no difference in lipid peroxidation. Antioxidant capacity declined from baseline to week 10 under all treatments. These results provide further evidence that short-wavelength light at night is a potent suppressor of nocturnal melatonin. Importantly, we also illustrate that shifting the spectral output to longer wavelengths could mitigate these negative physiological impacts.

show abstract

Section: Discussionmentioning

confidence: 99%

Artificial light pollution: Shifting spectral wavelengths to mitigate physiological and health consequences in a nocturnal marsupial mammal

Dimovski

Robert

2018

J Exp Zool Pt A

View full text Add to dashboard Cite

show abstract

“…Short term light treatments (e.g. two nights of half an hour) have also been used in combination with high light intensity (450 lux) 38 . Two nights of ALAN may thus induce effects on oxidative status but limit the risk of any nest abandonment 46 .…”

Section: Methodsmentioning

confidence: 99%

“…ref. 38 ), we took into account that in birds, and especially in great tits, there may be sex-specific differences in oxidative status, growth rate 39 40 and environmental sensitivity (reviewed in ref. 41 ), and we therefore used both male and female nestlings.…”

mentioning

confidence: 99%

Artificial light at night affects body mass but not oxidative status in free-living nestling songbirds: an experimental study

Raap

Casasole

Costantini

et al. 2016

Sci Rep

View full text Add to dashboard Cite

Artificial light at night (ALAN), termed light pollution, is an increasingly important anthropogenic environmental pressure on wildlife. Exposure to unnatural lighting environments may have profound effects on animal physiology, particularly during early life. Here, we experimentally investigated for the first time the impact of ALAN on body mass and oxidative status during development, using nestlings of a free-living songbird, the great tit (Parus major), an important model species. Body mass and blood oxidative status were determined at baseline (=13 days after hatching) and again after a two night exposure to ALAN. Because it is very difficult to generalise the oxidative status from one or two measures we relied on a multi-biomarker approach. We determined multiple metrics of both antioxidant defences and oxidative damage: molecular antioxidants GSH, GSSG; antioxidant enzymes GPX, SOD, CAT; total non-enzymatic antioxidant capacity and damage markers protein carbonyls and TBARS. Light exposed nestlings showed no increase in body mass, in contrast to unexposed individuals. None of the metrics of oxidative status were affected. Nonetheless, our study provides experimental field evidence that ALAN may negatively affect free-living nestlings’ development and hence may have adverse consequences lasting throughout adulthood.

show abstract

“…Birds are sensitive to light and can receive light information through retinal and nonretinal light receptors, thus causing metabolic changes ( Wilson, 2011 ). Light at night is a stressor that influences oxidative stress, which can cause the change of redox state in mice liver ( Ashkenazi and Haim, 2013 ). Compared with a single light, blue-green mixed-light significantly improved the serum glucose level of birds ( Yang et al, 2016 ).…”

Section: Discussionmentioning

confidence: 99%

Influence of light supplement on duck sternal calcification from integrated analysis of metabolome and transcriptome

Liu

Qunfang

et al. 2022

Poultry Science

View full text Add to dashboard Cite

Effect of Light at Night on oxidative stress markers in Golden spiny mice (Acomys russatus) liver

Cited by 9 publications

References 57 publications

Artificial light pollution: Shifting spectral wavelengths to mitigate physiological and health consequences in a nocturnal marsupial mammal

Artificial light pollution: Shifting spectral wavelengths to mitigate physiological and health consequences in a nocturnal marsupial mammal

Artificial light at night affects body mass but not oxidative status in free-living nestling songbirds: an experimental study

Influence of light supplement on duck sternal calcification from integrated analysis of metabolome and transcriptome

Contact Info

Product

Resources

About