Effect of material, process parameters, and simulated body fluids on mechanical properties of 13-93 bioactive glass porous constructs made by selective laser sintering

Kolan, Krishna C. R.; Leu, Ming C.; Hilmas, Greg; Vélez, Mariano

doi:10.1016/j.jmbbm.2012.04.001

Cited by 92 publications

(49 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Frozen vials of approximately 1 × 10 6 ASCs were obtained from three separate donors (LaCell, New Orleans, Louisiana, USA). Vials were unthawed, plated on 150 cm 2 culture dishes (Nunc, Rochester, New York, USA) in 25 mL complete culture media (CCM), and incubated at with 5% humidified CO 2 .…”

Section: Preparation Of Bio-inkmentioning

confidence: 99%

“…Additive manufacturing D (AM), or popularly known as 3D printing, is a layer-by-layer material deposition process in which functional parts with complex shapes can be made which are otherwise difficult to manufacture. AM of biomaterials has shown that complex and strong implants can be made to treat different regions of bone, including load-bearing bone [5][6][7] . However, engineered bone scaffolds have not been as successful as autologous grafts thus far, largely due to insufficient vascularization and reduced biomechanical function [8][9] .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

3D bioprinting of stem cells and polymer/bioactive glass composite scaffolds for bone tissue engineering

Murphy

Kolan

et al. 2017

ijb

126

View full text Add to dashboard Cite

A major limitation of using synthetic scaffolds in tissue engineering applications is insufficient angiogenesis in scaffold interior. Bioactive borate glasses have been shown to promote angiogenesis. There is a need to investigate the biofabrication of polymer composites by incorporating borate glass to increase the angiogenic capacity of the fabricated scaffolds. In this study, we investigated the bioprinting of human adipose stem cells (ASCs) with a polycaprolactone (PCL)/bioactive borate glass composite. Borate glass at the concentration of 10 to 50 weight %, was added to a mixture of PCL and organic solvent to make an extrudable paste. ASCs suspended in Matrigel were ejected as droplets using a second syringe. Scaffolds measuring 10x10x1 mm3 in overall dimensions with pore sizes ranging from 100 – 300 µm were fabricated. Degradation of the scaffolds in cell culture medium showed a controlled release of bioactive glass for up to two weeks. The viability of ASCs printed on the scaffold was investigated during the same time period. This 3D bioprinting method shows a high potential to create a bioactive, highly angiogenic three-dimensional environment required for complex and dynamic interactions that govern the cell’s behavior in vivo.

show abstract

Section: Preparation Of Bio-inkmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

3D bioprinting of stem cells and polymer/bioactive glass composite scaffolds for bone tissue engineering

Murphy

Kolan

et al. 2017

ijb

126

View full text Add to dashboard Cite

show abstract

“…In the SLS method, material properties and process factors such as laser energy density, part bed temperature, layer thickness, and hatch distance affect the structural and mechanical properties of fabricated parts [17, 18]. …”

Section: Laser Sintering Technologymentioning

confidence: 99%

A review on powder-based additive manufacturing for tissue engineering: selective laser sintering and inkjet 3D printing

Shirazi

Gharehkhani

Mehrali

et al. 2015

Science and Technology of Advanced Materials

579

324

View full text Add to dashboard Cite

Since most starting materials for tissue engineering are in powder form, using powder-based additive manufacturing methods is attractive and practical. The principal point of employing additive manufacturing (AM) systems is to fabricate parts with arbitrary geometrical complexity with relatively minimal tooling cost and time. Selective laser sintering (SLS) and inkjet 3D printing (3DP) are two powerful and versatile AM techniques which are applicable to powder-based material systems. Hence, the latest state of knowledge available on the use of AM powder-based techniques in tissue engineering and their effect on mechanical and biological properties of fabricated tissues and scaffolds must be updated. Determining the effective setup of parameters, developing improved biocompatible/bioactive materials, and improving the mechanical/biological properties of laser sintered and 3D printed tissues are the three main concerns which have been investigated in this article.

show abstract

“…Fracture toughness (K IC ) and Vickers hardness (H v ) were measured by the indentation method using Vickers hardness tester (TMVS-1, Beijing times Co., China) with the load of 2.94 N for 30 s. The crack length obtained was automatically recorded. Then the fracture toughness was expressed through the following equation [29]:…”

Section: Sample Characterizationmentioning

confidence: 99%

Selective laser sintering of β-TCP/nano-58S composite scaffolds with improved mechanical properties

et al. 2015

View full text Add to dashboard Cite

Effect of material, process parameters, and simulated body fluids on mechanical properties of 13-93 bioactive glass porous constructs made by selective laser sintering

Cited by 92 publications

References 36 publications

3D bioprinting of stem cells and polymer/bioactive glass composite scaffolds for bone tissue engineering

3D bioprinting of stem cells and polymer/bioactive glass composite scaffolds for bone tissue engineering

A review on powder-based additive manufacturing for tissue engineering: selective laser sintering and inkjet 3D printing

Selective laser sintering of β-TCP/nano-58S composite scaffolds with improved mechanical properties

Contact Info

Product

Resources

About