Effect of method of preparation on properties of temperature and pH-sensitive gels: Chemical crosslinking versus irradiation with e-beam

Lugo-Medina, Eder; Licea‐Claveríe, Angel; Cornejo-Bravo, José Manuel; Arndt, Karl‐Friedrich

doi:10.1016/j.reactfunctpolym.2006.09.003

Cited by 15 publications

(4 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In contrast to examples in the literature, no sharp increase in the water contact angle is observed. Lugo-Medina et al 27 also described this phenomenon. They explained the continuous increase in water contact angle with cross-linking within the films.…”

Section: B Plasma Copolymerizationmentioning

confidence: 85%

Deposition of Thermoresponsive Plasma Polymer Films from N-Isopropylacrylamide Using Dielectric Barrier Discharge at Atmospheric Pressure

et al. 2012

View full text Add to dashboard Cite

Thermoresponsive polymers are of great interest as functional coatings in biomedical applications. Poly-N-isopropylacrylamide (NiPAAm) is a widely used compound that switches its surface properties from hydrophilic to hydrophobic by passing the lower critical solution temperature of 32°C. This study investigated plasma polymerization of NiPAAm (pp-NiPAAm) using a dielectric barrier discharge. The films' chemical composition, thermoresponsive behavior, and stability in water were analyzed. Small effects with regard to thermoresponsive behavior were observed for films with high retention of the monomer structure. Unfortunately, however, these films were not stable in water, so plasma copolymerization was performed to improve film stability. Two different monomers were chosen: vinyltrimethoxysilane and glycidyl methacrylate. Thin films of pp-NiPAAM-co-glycidyl methacrylate show thermoresponsive behavior. While stability in water was improved significantly, the responsive behavior was lost after storing these films in water. Future work to ensure the long-term stability of pp-NiPAAm films, particularly in an aqueous environment, has to be done.

show abstract

Section: B Plasma Copolymerizationmentioning

confidence: 85%

Deposition of Thermoresponsive Plasma Polymer Films from N-Isopropylacrylamide Using Dielectric Barrier Discharge at Atmospheric Pressure

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Radiation polymerization is a cross-linking method that generates free radicals from monomers [ 86 ]. Amin et al prepared temperature and pH-responsive hydrogels by electron beam irradiation using bacterial cellulose (BC) and acrylic acid (AA) as monomers [ 65 ].…”

Section: Preparation Methods Of Smart Hydrogelsmentioning

confidence: 99%

Recent Advances in Smart Hydrogels Prepared by Ionizing Radiation Technology for Biomedical Applications

et al. 2022

View full text Add to dashboard Cite

Materials with excellent biocompatibility and targeting can be widely used in the biomedical field. Hydrogels are an excellent biomedical material, which are similar to living tissue and cannot affect the metabolic process of living organisms. Moreover, the three-dimensional network structure of hydrogel is conducive to the storage and slow release of drugs. Compared to the traditional hydrogel preparation technologies, ionizing radiation technology has high efficiency, is green, and has environmental protection. This technology can easily adjust mechanical properties, swelling, and so on. This review provides a classification of hydrogels and different preparation methods and highlights the advantages of ionizing radiation technology in smart hydrogels used for biomedical applications.

show abstract

“…36,37 This procedure successfully prevented lateral surface inhomogeneities and did not cause any cross-linking of the copolymer chains. The latter processes were reported to occur in other immobilisation strategies like chemical crosslinking and plasma immobilisation 30,38 and often disturb the desired phase transition. Since the carboxylic acid groups are statistically distributed over the copolymer chains, multiple binding sites are possible.…”

Section: Preparation Of Pnipaam Copolymer Grafted Substratesmentioning

confidence: 99%

“…23,26 However, it is known that the phase transition behaviour of SRP can be drastically altered if they are attached to solid supports: grafting, cross-linking density, and intermolecular forces from the supporting substrate can affect the phase transition behaviour. [27][28][29][30] The choice of the immobilisation method can be critically important for the conservation of the desired responsive characteristics of the SRP. Different grafting-from and grafting-to approaches were previously studied.…”

Section: Introductionmentioning

confidence: 99%

Tuneable swelling of thermo- and pH-responsive copolymer films

et al. 2010

View full text Add to dashboard Cite

We report on thermo-and pH-responsive copolymer films consisting of N-isopropylacrylamide (NIPAAm) and different carboxyalkylacrylamides exhibiting switchable swelling states over a wide range of temperatures and pH-values. The copolymers were covalently grafted as brush-like films onto solid substrates. Analysis by quartz crystal microbalance with dissipation monitoring revealed the phase transition behaviour to be sensitively controlled by the balance of polar and non-polar interactions, which could be dissected into the local level of comonomer structure as well as the more global level of copolymer chain composition. Remarkably, the phase transition was determined to be in general lower than in solution, which originated from the higher local polymer concentration of the swollen surface-grafted copolymer layer as explained by the general phase behaviour based on classical theory of polymers in solutions. The different swelling profiles of the environmentally responsive copolymer films are expected to offer valuable options for the design of switchable interfaces as, for instance, applicable for the modulation of model biosystems.

show abstract

Effect of method of preparation on properties of temperature and pH-sensitive gels: Chemical crosslinking versus irradiation with e-beam

Cited by 15 publications

References 29 publications

Deposition of Thermoresponsive Plasma Polymer Films from N-Isopropylacrylamide Using Dielectric Barrier Discharge at Atmospheric Pressure

Deposition of Thermoresponsive Plasma Polymer Films from N-Isopropylacrylamide Using Dielectric Barrier Discharge at Atmospheric Pressure

Recent Advances in Smart Hydrogels Prepared by Ionizing Radiation Technology for Biomedical Applications

Tuneable swelling of thermo- and pH-responsive copolymer films

Contact Info

Product

Resources

About