Effect of PEG addition on pore morphology and biocompatibility of PLLA scaffolds prepared by freeze drying

Mechanical properties and cytotoxicity of PLA/PCL films

“…The biodegradable polymers have been focused on as the candidate material of choice for environmental and biomedical applications, because of their excellent mechanical properties and biodegradability [1][2][3][4][5][6][7][8]. It is desirable to develop the renewable and biodegradable environmental materials to solve the problem caused by rapidly increasing disposable packaging materials designed for food and drugs [1].…”

Effect of polyethylene glycol molecular weight on cell growth behavior of polyvinyl alcohol/carboxymethyl cellulose/polyethylene glycol hydrogel

“…The pore size was then determined by using the optical microscope equipped with the iSolution Lite image software. [13][14][15][16][17][18][19][20][21] Compressive strength of the irradiated PVA/ CMC hydrogels was examined by using an Instron 5564 with a crosshead speed of 10 mm/min. The specimen with a diameter of 15 mm and a thickness of 5 mm was fabricated and the strength was determined at a point where the specimen thickness decreased by 50%.…”

“…The extract test method was conducted on the irradiated PVA/CMC/PEG hydrogels to evaluate the potential of cytotoxicity according to the International Organization for Standardization (ISO 10993-5). [13][14][15][16][17][18][19][20][21] The hydrogels were extracted aseptically in single strength minimum essential medium (1× MEM, Dulbecco's modified Eagle's medium [Gibco, Paisley, United Kingdom] with 10% fetal bovine serum [Gibco, Paisley, United Kingdom] and 1% penicillin-streptomycin) with serum. The ratio of the hydrogels to the extraction vehicle was 0.1 g/ml (ISO 10993-12).…”

“…Detailed experimental procedures are described elsewhere. [4,5,[13][14][15][16][17][18][19][20][21] Cell counting kit-8 (CCK-8, Dojindo Molecular Technologies, Inc., Rockville, MD, USA) is used for the assay of cell proliferation. CCK-8, being nonradioactive, allows sensitive colorimetric assays for the determination of the number of viable cells in cell proliferation.…”

“…CCK-8, being nonradioactive, allows sensitive colorimetric assays for the determination of the number of viable cells in cell proliferation. [13][14][15][16][17][18][19][20][21] Watersoluble tetrazolium salts were reduced by dehydrogenases in cells to give an orange colored product (formazan), which is soluble in the tissue culture medium. The amount of the formazan dye generated by dehydrogenases in cells is directly proportional to the number of living cells.…”