Effect of Phytoestrogen (Fennel) on Some Sex Hormones and Other Physiological Parameters in Male Albino Rats

Helal, Eman G.E.; Jalaud, Nora Abdulaziz Al; El-Aleem, Mohamed A.; Ahmed, Shaimaa S.

doi:10.21608/ejhm.2019.28268

Cited by 3 publications

(2 citation statements)

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“…Its seeds are used as a flavoring agent in food or traditional medicine and consumed as a medicinal tea. Traditionally, fennel has been used as an appetite suppressant to ease childbirth, increase milk secretion, promote menstruation, ease male menopause, and increase libido [ 94 , 95 , 96 , 97 ].…”

Section: Medicinal Plant-based Foods Recommended For the Treatment Of Dmmentioning

confidence: 99%

Protective Effects of Medicinal Plant-Based Foods against Diabetes: A Review on Pharmacology, Phytochemistry, and Molecular Mechanisms

et al. 2023

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Diabetes mellitus (DM) comprises a range of metabolic disorders characterized by high blood glucose levels caused by defects in insulin release, insulin action, or both. DM is a widespread condition that affects a substantial portion of the global population, causing high morbidity and mortality rates. The prevalence of this major public health crisis is predicted to increase in the forthcoming years. Although several drugs are available to manage DM, these are associated with adverse side effects, which limits their use. In underdeveloped countries, where such drugs are often costly and not widely available, many people continue to rely on alternative traditional medicine, including medicinal plants. The latter serves as a source of primary healthcare and plant-based foods in many low- and middle-income countries. Interestingly, many of the phytochemicals they contain have been demonstrated to possess antidiabetic activity such as lowering blood glucose levels, stimulating insulin secretion, and alleviating diabetic complications. Therefore, such plants may provide protective effects that could be used in the management of DM. The purpose of this article was to review the medicinal plant-based foods traditionally used for the management of DM, including their therapeutic effects, pharmacologically active phytoconstituents, and antidiabetic mode of action at the molecular level. It also presents future avenues for research in this field.

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Section: Medicinal Plant-based Foods Recommended For the Treatment Of Dmmentioning

confidence: 99%

Protective Effects of Medicinal Plant-Based Foods against Diabetes: A Review on Pharmacology, Phytochemistry, and Molecular Mechanisms

et al. 2023

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“…In other studies, purslane extract increased activity levels of superoxide dismutase (SOD) and decreased levels of malondialdehyde (MDA) in an ulcerative colitis mouse model [ 22 ]. F. vulgare mill, also known as fennel, is an aromatic Mediterranean plant that has received much attention in traditional medicine [ 23 , 24 ]. This medicinal plant has diuretic, analgesic, anti-inflammatory, antipyretic, and antioxidant activity [ 25 , 26 ].…”

Section: Introductionmentioning

confidence: 99%

The effects of purslane (Portulaca oleracea) and fennel (Foeniculum vulgare Mill) hydroalcoholic extracts on the functional parameters of human spermatozoa after vitrification

Torkamanpari

Ghorbani

Lorian

et al. 2023

Clin Exp Reprod Med

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Objective: Reactive oxygen species (ROS) are produced during cryopreservation of human sperm and impair sperm function. Antioxidant compounds, such as fennel and purslane, reduce the damaging effects of ROS. This study aimed to evaluate motility parameters, plasma membrane integrity (PMI), mitochondrial membrane potential (MMP), intracellular ROS, and DNA damage to determine the optimum concentrations of hydroalcoholic extracts of fennel and purslane for human spermatozoa cryopreservation. Methods: Twenty human sperm samples were used and divided into seven equal groups consisting of fennel hydroalcoholic extract (5, 10, and 15 mg/L), purslane hydroalcoholic extract (25, 50, and 100 mg/L), and no additive. Results: Supplementation of 25 mg/L and 50 mg/L purslane extract and 10 mg/L fennel extract in cryopreservation extender significantly increased the motility and PMI of sperm with a significant reduction in intracellular ROS compared to control groups (p<0.05). A 50 mg/L concentration of purslane extract elevated progressive motility and MMP compared to the control group (p<0.05). No significant differences were seen for motion patterns and DNA damage of frozen–thawed human sperm in extender containing these extracts. Conclusion: The results showed that supplementation of 50 mg/L purslane extract and 10 mg/L fennel extract in semen cryopreservation extender has the potential to decrease intracellular ROS and subsequently elevate the motility and PMI of human sperm.

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Biomaterials as regenerative medicine in Poly Cystic Ovarian Syndrome (PCOS) treatment

Chauhan

Peter²,

Soni³

et al. 2022

Biochemical Engineering Journal

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Effect of Phytoestrogen (Fennel) on Some Sex Hormones and Other Physiological Parameters in Male Albino Rats

Cited by 3 publications

References 0 publications

Protective Effects of Medicinal Plant-Based Foods against Diabetes: A Review on Pharmacology, Phytochemistry, and Molecular Mechanisms

Protective Effects of Medicinal Plant-Based Foods against Diabetes: A Review on Pharmacology, Phytochemistry, and Molecular Mechanisms

The effects of purslane (Portulaca oleracea) and fennel (Foeniculum vulgare Mill) hydroalcoholic extracts on the functional parameters of human spermatozoa after vitrification

Biomaterials as regenerative medicine in Poly Cystic Ovarian Syndrome (PCOS) treatment

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