2012
DOI: 10.4103/2045-080x.116604
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Effect of polymers on in-vitro performance of eplerenone sustained release matrix tablets

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“…Other studies reported similar results that the drug release rate decreased with increasing molecular weight for low molecular weight HPMCs and became independent of molecular weight for high molecular weight HPMCs. [27][28] In the case of 60% HPMC K100M formulations (H19) also, the release profiles followed similar trend as in the case of H4 (K100LV) formulations. The reason for the present findings can be explained as follows.…”
Section: Discussionsupporting
confidence: 52%
“…Other studies reported similar results that the drug release rate decreased with increasing molecular weight for low molecular weight HPMCs and became independent of molecular weight for high molecular weight HPMCs. [27][28] In the case of 60% HPMC K100M formulations (H19) also, the release profiles followed similar trend as in the case of H4 (K100LV) formulations. The reason for the present findings can be explained as follows.…”
Section: Discussionsupporting
confidence: 52%