This paper is aimed at studying the influence of the competitive adsorbates (HCl, lactic acid, and citric acid) on the structural and catalytic properties of PtSnNaMg/ZSM-5 catalysts for propane dehydrogenation. N 2 adsorption, X-ray diffraction, inductively coupled plasma, NH 3 temperature-programmed desorption, H 2 temperature-programmed reduction and transmission electron microscopy were applied for characterization of the prepared catalysts. The catalytic performance was tested in a microreactor. The obtained results indicate that the catalyst prepared in HCl medium exhibited the best catalytic activity and stability due to relatively better metal distribution on the support and/or the strong interactions between Pt and Sn as well as between them and the support.