BackgroundThe direction of the current research was to investigate whether electrocardiogram (ECG) signals have been impacted by using compression garments during exercise and recovery phase. Each subject is non-athletes, conducted two running tests, wearing either non-compression garments (NCGs) or compression garments (CGs) throughout experiments and 2-h of the recovery phase. Experiment 1 (number of participants (n) = 8; 61.4 ± 13.7 kg, 25.1 ± 3.8 years, 165.9 ± 8.3 cm) focused on the exercising phase while Experiment 2 (n = 14; 60.9 ± 12.0 kg, 24.7 ± 4.5 years, 166.0 ± 7.6 cm) concentrated on the recovery phase. Electrocardiogram (ECG) data were collected through wearable biosensors.ResultsThe results demonstrated a significant difference between compression garments and non-compression garments at the end of the tests and from 90 min onwards during the recovery phase (p < 0.05). Corrected QT (QTc), ST interval and heart rate (HR) indicated the significant difference between NCGs and CGs. Conclusion: Based on the findings, the utilization of compression garments showed a positive influence in non-athletes based on the quicker recovery in HR, ST, and QTc.