Effect of zinc oxide and zirconia on structure, degradability and in vitro bioactivity of wollastonite

Li, H.C.; Wang, Diangang; Chen, C.Z.

doi:10.1016/j.ceramint.2015.04.117

Cited by 43 publications

(17 citation statements)

References 60 publications

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“…The phase formation of the samples NCS and CCS which were sintered at 802°C and 900°C, respectively, were examined by XRD. The XRD peak patterns (Figure ) of both the samples showed very similar trend and well matched with JCPDS file no: 84‐0655 of β ‐wollastonite phase . It is also noticed that the peak intensities of NCS powder were slightly higher than that of CCS; this observation indicates that the calcium silicate synthesized from RHA and eggshell has good crystallization.…”

Section: Resultssupporting

confidence: 70%

“…The XRD peak patterns ( Figure 2) of both the samples showed very similar trend and well matched with JCPDS file no: 84-0655 of β-wollastonite phase. 28 It is also noticed that the peak intensities of NCS powder were slightly higher than that of CCS; this observation indicates that the calcium silicate synthesized from RHA and eggshell has good crystallization. The average crystallite size was calculated as ~48.3 nm for NCS and ~62.8 nm for CCS using Debye Scherrer's equation.…”

Section: Structural Characterizationmentioning

confidence: 89%

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A comparative study on in vitro behavior of calcium silicate ceramics synthesized from biowaste resources

et al. 2019

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Calcium silicate ceramics have received significant attention for biomedical applications for their excellent bioactivity and osteoconduction properties. Sol‐gel process is extensively used for the fabrication of calcium silicates. In sol‐gel process, calcium nitrate tetra hydrate (Ca(NO3)2·4H2O) and tetraethylorthosilicate (TEOS) are used as precursors. However, these precursors are expensive. The objective of this work was to compare in vitro behavior of calcium silicate (CaSiO3) produced using biowaste such as rice husk ash (RHA) and eggshells (coded; NCS) with CaSiO3 prepared using TEOS and Ca(NO3)2·4H2O (coded; CCS). Thermal investigation results revealed that the crystallization temperature for NCS is relatively lower (772°C) than for CCS (870°C). Bioactivity was studied in vitro using simulated body fluid (SBF) with respect to mineralization rate of hydroxyapatite. Mineralization of a greater hydroxyapatite was observed on NCS ceramics than CCS ceramics after incubation for 3, 7, 14 days in SBF solution, which was confirmed using X‐ray diffractometer, Fourier transform infrared spectroscopy, scanning electron microscopy‐energy dispersive spectroscopy. Degradation studies were conducted in Tris‐HCl solution and the test results revealed that NCS ceramics has lower dissolution rate than CCS ceramics. The antimicrobial assay has shown that NCS samples exhibit significant zone of inhibition against Escherichia coli and Staphylococcus aureus which confirmed that the CaSiO3 prepared from RHA and eggshell can prevent bacteria from adhering to the surface. In addition cell culture studies revealed that NCS ceramics possess good cytocompatibility with MG‐63 cells and significantly promoted cell proliferation.

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Section: Resultssupporting

confidence: 70%

Section: Structural Characterizationmentioning

confidence: 89%

A comparative study on in vitro behavior of calcium silicate ceramics synthesized from biowaste resources

et al. 2019

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“…In order to improve the mechanical and degradation properties of bioactive CaO-SiO 2 systems, Li et al investigated the effect of partially substituting CaO with ZnO [ 100 ]. The considered bioceramics were prepared by sintering a sol-gel derived precursor, including zinc nitrate hexahydrate to substitute 5 mol % of ZnO for CaO.…”

Section: Zno-based Composite Materialsmentioning

confidence: 99%

ZnO Nanostructures for Tissue Engineering Applications

2017

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This review focuses on the most recent applications of zinc oxide (ZnO) nanostructures for tissue engineering. ZnO is one of the most investigated metal oxides, thanks to its multifunctional properties coupled with the ease of preparing various morphologies, such as nanowires, nanorods, and nanoparticles. Most ZnO applications are based on its semiconducting, catalytic and piezoelectric properties. However, several works have highlighted that ZnO nanostructures may successfully promote the growth, proliferation and differentiation of several cell lines, in combination with the rise of promising antibacterial activities. In particular, osteogenesis and angiogenesis have been effectively demonstrated in numerous cases. Such peculiarities have been observed both for pure nanostructured ZnO scaffolds as well as for three-dimensional ZnO-based hybrid composite scaffolds, fabricated by additive manufacturing technologies. Therefore, all these findings suggest that ZnO nanostructures represent a powerful tool in promoting the acceleration of diverse biological processes, finally leading to the formation of new living tissue useful for organ repair.

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“…Low mechanical strength (less than the cortical bone), brittleness, and low handiness (difficulty to cut under operating conditions) are a problem in clinical conditions. However, modifications in the chemical structure of apatite (Si, Sr, Fe, and Mg ion substitution) and bioglass (addition of MgO, SrO, or ZnO oxides) allow to achieve better structural mimetics of the substitute, but do not significantly improve its mechanical properties while maintaining high bioactivity [ 15 , 16 , 17 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

How Surface Properties of Silica Nanoparticles Influence Structural, Microstructural and Biological Properties of Polymer Nanocomposites

et al. 2021

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The aim of this work was to study effect of the type of silica nanoparticles on the properties of nanocomposites for application in the guided bone regeneration (GBR). Two types of nanometric silica particles with different size, morphology and specific surface area (SSA) i.e., high specific surface silica (hss-SiO2) and low specific surface silica (lss-SiO2), were used as nano-fillers for a resorbable polymer matrix: poly(L-lactide-co-D,L-lactide), called PLDLA. It was shown that higher surface specific area and morphology (including pore size distribution) recorded for hss-SiO2 influences chemical activity of the nanoparticle; in addition, hydroxyl groups appeared on the surface. The nanoparticle with 10 times lower specific surface area (lss-SiO2) characterized lower chemical action. In addition, a lack of hydroxyl groups on the surface obstructed apatite nucleation (reduced zeta potential in comparison to hss-SiO2), where an apatite layer appeared already after 48 h of incubation in the simulated body fluid (SBF), and no significant changes in crystallinity of PLDLA/lss-SiO2 nanocomposite material in comparison to neat PLDLA foil were observed. The presence and type of inorganic particles in the PLDLA matrix influenced various physicochemical properties such as the wettability, and the roughness parameter note for PLDLA/lss-SiO2 increased. The results of biological investigation show that the bioactive nanocomposites with hss-SiO2 may stimulate osteoblast and fibroblast cells’proliferation and secretion of collagen type I. Additionally, both nanocomposites with the nanometric silica inducted differentiation of mesenchymal cells into osteoblasts at a proliferation stage in in vitro conditions. A higher concentration of alkaline phosphatase (ALP) was observed on the material modified with hss-SiO2 silica.

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Effect of zinc oxide and zirconia on structure, degradability and in vitro bioactivity of wollastonite

Cited by 43 publications

References 60 publications

A comparative study on in vitro behavior of calcium silicate ceramics synthesized from biowaste resources

A comparative study on in vitro behavior of calcium silicate ceramics synthesized from biowaste resources

ZnO Nanostructures for Tissue Engineering Applications

How Surface Properties of Silica Nanoparticles Influence Structural, Microstructural and Biological Properties of Polymer Nanocomposites

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