Objectives: To describe the self-care abilities and associated factors in chronic heart failure (CHF) patients. Methods: Participant characteristics, illness-related information, and self-care ability were investigated using self-report questionnaires and patient records for 91 CHF patients in Nantong University Affiliated Hospital, China. Results: On average, patients had medium-to low-level self-care abilities. Comprehensive self-care ability was positively influenced by higher education level, employment status, and income level. Patients who received health education and had sound heart function had better self-care abilities. Regression analysis showed that the factors influencing self-care ability included average monthly income, education level, and heart function grading. Conclusions: Self-care ability in CHF patients is, in general, in medium to low ranges, indicating that medical workers need to enhance self-care education for CHF patients to help them better understand their condition and help them gain the necessary skills for self-care. We conclude that, when conducting self-care education for patients, medical workers should tailor their approach based on the individual characteristics of the patient. Doing so would effectively promote patient knowledge, mobility, and treatment compliance.