Effectiveness of calcium hydroxide‐based intracanal medicaments against <i>Enterococcus faecalis</i>

Lima, Regina K. P.; Guerreiro-Tanomaru, Juliane Maria; Faria-Júnior, Norberto Batista de; Tanomaru-Filho, Mário

doi:10.1111/j.1365-2591.2011.01976.x

Cited by 52 publications

(58 citation statements)

References 34 publications

(96 reference statements)

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“…13,14,15,19 Calcium hydroxide paste has strong biological and antimicrobial properties due to its highly alkaline pH 8 and is considered the gold standard intracanal medication for treating endodontic infections. However, calcium hydroxide has disadvantages, such as its low potential against E. faecalis, 3,26 which can survive in dentin tubules for long periods in the presence of the antimicrobial agent. 18,26 Thus, in this study, the brown propolis extracts were mixed with calcium hydroxide to observe a possible improvement of the calcium hydroxide paste against E. faecalis.…”

Section: Discussionmentioning

confidence: 99%

“…However, calcium hydroxide has disadvantages, such as its low potential against E. faecalis, 3,26 which can survive in dentin tubules for long periods in the presence of the antimicrobial agent. 18,26 Thus, in this study, the brown propolis extracts were mixed with calcium hydroxide to observe a possible improvement of the calcium hydroxide paste against E. faecalis.…”

Section: Discussionmentioning

confidence: 99%

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In vitro effectiveness of Brazilian brown propolis against Enterococcus faecalis

et al. 2015

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The aim of this study was to evaluate the in vitro antimicrobial activity of Brazilian brown propolis as an intracanal medication against Enterococcus faecalis. Thirty dentin discs prepared from intact freshly extracted bovine maxillary central incisors were infected with E. faecalis for 21 days. The specimens were distributed into six groups according to the medicament used as follows: G1-calcium hydroxide paste; G2-Carbowax 400 (control group); G3-20% brown propolis paste; G4-40% brown propolis paste; G5-20% brown propolis paste + calcium hydroxide paste; and G6-40% brown propolis paste + calcium hydroxide paste. The experimental pastes were placed into the canal lumen and left for 14 days. After each period, irrigation was performed with sterile saline to remove the medicament, and the canals were dried with sterile paper points. The dentin chips were removed from the canals with sequential sterile round burs at low speed and were immediately collected in separate test tubes containing BHI broth. The tubes were incubated at 37°C, and microbial growth was analyzed by spectrophotometry after 15 days. All the experimental medications significantly reduced the number of viable bacteria. The G4 and G5 pastes were more effective than the G1 paste, with 35.8%, 41%, and 21.3% antibacterial activity, respectively. Brazilian brown propolis shows antibacterial capacity against E. faecalis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

In vitro effectiveness of Brazilian brown propolis against Enterococcus faecalis

et al. 2015

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“…The results of the present study demonstrated that the association with CHX favored the antibacterial activity of CH against E. faecalis. These results may be related to the reduction in E. faecalis adhesion to dentin 19,20 , and its sensitivity to CHX 10,17,21,22 .…”

Section: Discussionmentioning

confidence: 99%

“…faecalis biofilm induced in root canals for 21 days, allowed the propagation of the microorganisms into dentinal tubules and root canal system. Therefore, the methodology allowed evaluation of the antibacterial effect of the medications against the microorganisms into root canal systems 10 . The evaluated medications were effective in eliminating E. faecalis from main canal, as demonstrated in the post-medication sample (S2).…”

Section: Discussionmentioning

confidence: 99%

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Antibacterial activity of intracanal medications based on calcium hydroxide and zinc oxide micro- or nanoparticles: an ex vivo study

Guerreiro-Tanomaru

Aguiar

Chávez-Andrade

et al. 2017

Rev. odontol. UNESP

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Introduction Nanoparticles and associations to calcium hydroxide can be used to increase antimicrobial activity. Objective To evaluate antibacterial activity against Enterococcus faecalis and pH of intracanal medications (IM) based on calcium hydroxide (CH) and zinc oxide (ZnO) micro- or nanoparticles, and their association with 0.4% chlorhexidine (CHX). Material and method Root canals from single-rooted human teeth were inoculated and incubated for 21 days. After sample (S1), the root canals were filled with the medications for 7 days and samples were collected immediately after medication (S2) and 7 days later (S3). Counting of CFU mL-1 was performed. Polyethylene tubes filled with the medications were used for the pH evaluation after 3, 7, 14 and 28 days. Data were submitted to ANOVA and Tukey tests (p<0.05). Result All IM promoted elimination of E. faecalis immediately after medication (S2). All the pastes promoted a similar pH increase. Conclusion CH/ZnO micro- or nanoparticles associated with CHX promoted greater bacterial reduction in the root canals and similar pH.

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Intracanal Medication in Root Canal Disinfection

Silva

Nelson‐Filho

Cohenca

2014

Disinfection of Root Canal Systems

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Effectiveness of calcium hydroxide‐based intracanal medicaments against Enterococcus faecalis

Abstract: In this laboratory study using extracted teeth all calcium hydroxide-based medicaments were able to significantly reduce the CFU mL(-1) values of E. faecalis in the root canal system.

Cited by 52 publications

References 34 publications

In vitro effectiveness of Brazilian brown propolis against Enterococcus faecalis

In vitro effectiveness of Brazilian brown propolis against Enterococcus faecalis

Antibacterial activity of intracanal medications based on calcium hydroxide and zinc oxide micro- or nanoparticles: an ex vivo study

Intracanal Medication in Root Canal Disinfection

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