Dental and oral health problems in preschool children i.e. Early Chilhood Caries (ECC) is amounted to 90.05%. This is because the children have not been able to do the tooth brushing activities on their own. The modified Ireine’s Education Model reflects a model of change in dental hygiene behavior of preschool children in the habit of tooth brushing from an early age. Its aim is to improve the tooth brushing skills of preschool children with guidance from their teachers and parents. The aim of generating modified Ireine's Education Model is as an effort to improve the tooth brushing skills of preschool children. The study method Research and Development (R & D) with Quasy experiment. The subjects of the preschool children were divided into 2 groups: Intervention group with the modified Ireine's Education Model which was done for 21 days and control group with Phantom Media. The independent variable in this research is the modified Ireine's Education Model, while the dependent varibale is tooth brushing skills in preschool children. The data was tested using Intraclass corelation test coefficient, Anova, Shapiro Wilk, Wilcoxon, and Mann Whitney. The result indicates that the modified Ireine's Education Model is more effective raises the free score of preschool children plaque with p-value in less than 0.001. Furthermore, it improves their tooth brushing skills with p-value in less than 0.010 compared to the control group. In conclusion, the modified Ireine's Education Model is more effectively improves the skills of brushing in preschool children as opposed to phantom media.