Effectiveness of polyacrylic acid-bioactive glass air abrasion preconditioning with NovaMin remineralization on the microhardness of incipient enamel-like lesion

Abstract

Background: Bioactive glass (BAG) remineralization is a promising method for dental hard tissue regeneration. The aim of this study was to evaluate the microhardness of incipient enamel-like lesions with or without preconditioning by air abrasion using polyacrylic acid (PAA)-BAG before application of NovaMin remineralizing agent. Materials and Methods: Forty extracted human molars were selected, sectioned mesiodistally obtaining buccal and lingual halves, and embedded in resin molds. Specimens were randomly assigned to four groups ( n = 10) according to the remineralization protocol: G1 (control, artificial saliva), G2 (preconditioning), G3 (NovaMin), and G4 (preconditioning and NovaMin). Enamel windows 4 mm × 4 mm were done on the buccal and lingual surfaces. Specimens were immersed in a daily renewed demineralizing solution to create white spot lesions. Remineralizing agents were applied according to the manufacturer's instructions, and specimens were stored in a daily renewed artificial saliva. Microhardness was assessed using Vickers hardness number (VHN) at baseline (positive control), after demineralization (negative control), and after 24-h and 1-month remineralization. Results: The preconditioning/NovaMin group after 1 month showed a statistically significant high VHN, with no statistically significant difference between it and the positive control. This was followed by the NovaMin group after 1 month, while the lowest VHN was found in the demineralized group, with no statistically significant difference between it and the preconditioning group, whether after 24 h or 1 month. Conclusions: Enamel preconditioning with PAA-BAG air abrasion play a major role in enhancement of remineralization when it is accompanied with NovaMin. Furthermore, an extended period of time had helped to attain more benefits from NovaMin remineralization. Clinical Significance: Enamel remineralization with NovaMin after conditioning by bioactive glass air abrasion, provides the patients with a fast and durable treatment of incipient enamel lesions, which would reduce the possibility of future progression of demineralization and caries occurrence.

Comparative evaluation of four different remineralizing agents on dentin surface topography: an invitro study

“…The results of this study is in agreement with Alafifi et al (21) who found that using Nano-hydroxyapatite has the ability to occlude the opened dentinal tubules because of the size of the nanoparticles which was smaller than the size of the dentinal tubules, it is possible that the carbonated apatite nanoparticles adhered to opened dentinal tubules. In addition, the nano-sized particles have an affinity and can induce deposition on irregular spaces (22) .…”

Remineralization of early enamel lesions with a novel prepared tricalcium silicate paste

“…In both scores, the structural integrity of the enamel is maintained and intact with no localized breakdown. When these lesions are left untreated, they might progress to a continuous loss of minerals and break down until cavitation 2 . Current cariology research focused on the effectiveness of the application of some remineralizing agents that maintained ion supersaturation in the oral environment surrounding these lesions.…”

Effect of (CPP-ACP) and (CPP-ACP with fluoride) on Chemical and Morphological Analysis of Bovine Teeth Following Demineralization/Remineralization Cycles” An In-vitro Study

“…In calcium / phosphorous ratio MI Paste decreased with (-0.52 ± 0.26) and MI Paste Plus decreased with (-0.55 ± 0.05). Comparison between both groups was performed by using independent t-test revealed insignificant difference between them as P<0.05, as presented in table (2) and figure (6).…”

“…In calcium / phosphorous ratio MI Paste increased with (0.37 ± 0.14) and MI Paste Plus decreased with (0.57 ± 0.01). Comparison between both groups was performed by using Independent t-test revealed significant difference between them as P < 0.05 (MI Paste Plus was significantly higher than MI Paste in calcium, phosphorous and calcium / phosphorous ratio), as presented in table (2) and figure (6).…”

“…The equilibrium between demineralization and remineralization process, are affected by pathological factors and protective factors that determine the fate of the lesion (1). If these demineralized lesions kept untreated, further progress of minerals loss might occur and breakdown until cavitation (2).…”