Effects of aloe vera gel application on epidermal wound healing in the domestic rabbit

Kayode, Olaifa Abayomi

doi:10.18203/2320-6012.ijrms20164531

Cited by 8 publications

(5 citation statements)

References 17 publications

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“…Several other studies have also reported on biochemical studies that Aloe vera has revealed significant increase in collagen and decreased hexosamine content and malondialdehyde levels when compared with control (Yadav et al, 2012). The same thing is also shown by (Kayode, 2016) who has tested the effect of Aloe vera gel application on epidermal wound healing in the domestic rabbit. The results showed that animals treated with Aloe vera gel had significantly (p<0.05) faster rates of healing with shorter days of scab fall off than the control and showed significant (P<0.05) changes in the packed cell volume, mean corpuscular volume, lymphocyte and neutrophil counts (Kayode, 2016).…”

Section: Results and Discussion Evaluation Results Of Aloe Vera Extrasupporting

confidence: 60%

Wound healing activity of aloe vera extract spray on acute wound in male balb/c mice

Sikumbang

Astuti²,

Wahyuningtyas³

et al. 2020

Pharmaciana

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Section: Results and Discussion Evaluation Results Of Aloe Vera Extrasupporting

confidence: 60%

Wound healing activity of aloe vera extract spray on acute wound in male balb/c mice

Sikumbang

Astuti²,

Wahyuningtyas³

et al. 2020

Pharmaciana

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“…The erythropoietin effects of A. vera extracts in hemotopoietic cells of bone marrow have been reported (Iji et al 2010). The assumption is that these effects could be due to vitamins such as beta carotene, C, E, B 12 , riboflavin, thiamine, and folic acid, minerals (calcium, chromium, copper, selenium, manganese, potassium, sodium, and zinc essential and nonessential amino acids) present in A. vera that are essential for the synthesis of hemoglobin as demonstrated in Kayode (2016). Erythropoiesis has also been attributed to polysaccharides present in A. vera leaves (Ni et al 2004).…”

Section: Discussionmentioning

confidence: 99%

Effect of dietary Aloe vera polysaccharides supplementation on growth performance, feed utilization, hemato-biochemical parameters, and survival at low pH in African catfish (Clarias gariepinus) fingerlings

et al. 2019

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This study evaluated the effects of dietary Aloe vera polysaccharides on growth performance, feed utilization, hemato-biochemical parameters, and resistance against low water pH in African catfish (Clarias gariepinus) fingerlings. Fish were divided into five triplicate groups before being fed feeds supplemented with 0% (control), 0.5%, 1.0%, 2.0%, and 4.0% A. vera/kg diet for 8 weeks. Fish fed 1.0% A. vera/kg diet had significantly increased (P \ 0.05) growth parameters (i.e., final weight, weight gain, absolute growth rate, and specific growth rate) compared to unsupplemented ones. Among dietary groups, significantly lower feed conversion ratio was presented in fish fed 1.0% followed by those fed 0.5, 2.0%, and 4.0% A. vera/kg diet (P \ 0.05). The protein efficiency ratio was significantly higher (P \ 0.05) in fish fed 1.0% A. vera/kg diet compared to unsupplemented fish and those fed 4.0% A. vera/kg diet, respectively. Dietary A. vera polysaccharide crude extracts requirement suitable for growth and feed utilization was estimated to be between 1.76 and 1.79% A. vera/kg diet. Overall, A. vera extracts had improved hemato-biochemical indices when compared to unsupplemented fish, and decreased some of the indices, especially at high dietary inclusion level (4%/kg diet). Furthermore, A. vera-supplemented fish had higher survival probability throughout the low water pH challenge period, except those fed 4% A. vera/kg diet and control diet.

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“…An aloe vera extract given to the rabbit wounds had significantly affected the wound contraction, especially in the proliferative and maturation phases. 17 There are also no studies that directly examine the effect of aloe vera extract in increasing the FGF expression levels on the wound healing process of hyperglycemic. Therefore, the present study is the first study that examined and compared the effects of Lagerstroemia speciosa and aloe vera on hyperglycemia-induced rats' wound healing process by observing the FGF-2 expression level.…”

Section: Discussionmentioning

confidence: 99%

Expression of fibroblast growth factor-2 after application of the Queen's crepe-myrtle leaf (Lagerstroemia speciosa) and aloe vera extract gel in the wound healing process of hyperglycemic

et al. 2021

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Introduction: Fibroblast Growth Factor-2 (FGF-2) have a role in stimulating the proliferation and migration of various types of cells in the wound healing process. Hyperglycemic conditions can disrupt the wound healing process. Lagerstroemia speciosa are known to have antyphyerglycemic and antioxidant effects. Aloe vera is a plant that has been used for long time in topical treatment of wounds.This study was aimed to analyse the FGF-2 expressions on the wound healing process of subjects with hyperglycemia after application of Queen's crepe-myrtle leaf (Lagerstroemia speciosa) and aloe vera extracts gel. Methods: A pure experimental study was conducted with simple random sampling. The sample was 27 experimental animals (CI 95%; power test 80%) of Sprague Dawley rat induced to have a hyperglycemic state using alloxan and had their palate injured. The immunohistochemical examination was performed to assess FGF-2 expression level. Samples were divided into three groups with a simple random sampling technique: nine of the rats received the Lagerstroemia speciosa extract gel application; nine rats received the aloe vera extract gel application on the injured palate; another nine rats in the control group. Examination of the FGF-2 expression level was performed on the third, seventh, and fourteenth observation days. Results: Overall, the control group had a significant difference with the Lagerstroemia speciosa and aloe vera extract gel group (p-value<0.05), however, the Lagerstroemia speciosa group did not have any significant difference with the aloe vera group (0.123>0.05). Conclusion: There was no difference in the amount of FGF-2 expressions on the wound healing process of the injured palatal tissue of Sprague-Dawley rats with hyperglycemic after application of the Lagerstroemia speciosa and aloe vera extract gel.

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Effects of aloe vera gel application on epidermal wound healing in the domestic rabbit

Cited by 8 publications

References 17 publications

Wound healing activity of aloe vera extract spray on acute wound in male balb/c mice

Wound healing activity of aloe vera extract spray on acute wound in male balb/c mice

Effect of dietary Aloe vera polysaccharides supplementation on growth performance, feed utilization, hemato-biochemical parameters, and survival at low pH in African catfish (Clarias gariepinus) fingerlings

Expression of fibroblast growth factor-2 after application of the Queen's crepe-myrtle leaf (Lagerstroemia speciosa) and aloe vera extract gel in the wound healing process of hyperglycemic

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