Effects of Dietary Nano-Zinc and Nano-Selenium Addition on Productive and Physiological Performance of Growing Rabbits at Fattening Period

Abstract

his study was designed to evaluate the effects of dietary Nano-zinc (Nano-Zn) and Nano-selenium (Nano-Se) supplementation on growth performance, nutrients utilization, carcass parameters and blood plasma biochemical in growing rabbits. A total of 50, six-week-old New Zealand White (NZW) rabbits of about 815 g l.b.w. were randomly distributed into five equal groups. The control group was fed on a basal diet without any supplement; the second and third groups were fed the basal diet supplemented with 30 and 60 mg Nano-Zn/kg, respectively, while the fourth and fifth groups were fed the basal diet supplemented with 0.1 and 0.3 mg Nano-Se/kg, respectively during the experimental period (6-12 wks of age).The results revealed that rabbits fed diet supplemented with different Nano-Zn or Nano-Se levels had higher (P>0.05) live body weight at 12 wks than the control. Moreover, body weight gain, feed conversion ratio and protein efficiency ratio were insignificantly improved comparing with the control group at the whole experimental period (6-12 wks of age), rabbits fed diet supplemented with 60 mg Nano-Zn or 0.3 mg Nano-Se/kg recorded the higher value of different growth parameters. All studied nutrients digestibility and carcass traits were not significantly affected by dietary treatment. No significant differences were observed among experimental rabbit groups in studied plasma parameters by dietary Nano-Zn or Nano-Se supplementation as compared with the control group. Results generally showed that the best results in most studied traits were recorded for dietary 60 mg Nano-zinc or 0.3 mg Nano-selenium / kg diet of growing rabbits during experimental period. Therefore, the addition of 60 mg Nano-Zn or 0.3 mg Nano-Se/kg diet may be an alternative method to maximize the productivity of growing NZW rabbits without adverse effects during fattening period.

Dietary supplementation of nano-selenium eliminates the negative effects of long-term ivermectin injection on growth and reproductive performance of female rabbits

“…It also protected the intestinal mucosa and improved its absorptive capacity, preventing diarrhea by decreasing the peristastic movement of the intestine [ 35 ]. In contrast to our results, of Abdel-Wareth et al [ 16 ], Tag-El Din [ 24 ], and El-Kazaz et al [ 36 ] revealed that nano-Se reduced the TFI in growing NZW rabbits, male Californian rabbits, and Japanese quails, respectively. Such variations may be attributed to using different doses, sex, or species.…”

“…Se is a crucial element that regulates the body’s energy, protein anabolism, and oxidative stress, allowing animals to develop and reproduce normally [ 28 ]. However, recent research reveals that the NRC Se standard of 0.08 mg/kg in a developing rabbit diet failed to meet the rabbit’s growth requirements and that high levels are required to optimize nutrient digestion, absorption, and utilization, which boosts productive and reproductive performance [ 13 , 24 , 28 ].…”

“…In line with the same trend, Emara et al [ 30 ] and Abdel-Wareth et al [ 16 ] reported an improvement in the growth rate, BW, and FCR of rabbits fed on nano-Se and explained this by improving the nutrient digestibility, antioxidative, and immune properties and increasing the serum active thyroid hormone level [ 31 ]. Similarly, Tag-El Din [ 24 ] reported that feeding nano-Se (0.3 mg/kg diet) showed the best growth performance and FCR of growing New Zealand White rabbits and attributed this to the high biological activity and immune regulation of nano-Se [ 32 ]. Mohapatra et al [ 10 ] indicated that pullets or broilers’ diets supplemented with 0.3 mg/kg nano-Se led to the best growth performance.…”

“…Animals were divided into four groups (21 does/group), and each group was divided into three replicates (seven does/replicate). The does were fed an isonitrogenous and isoenergetic basal diet containing all the required nutrients [ 23 ], except for selenium [ 24 , 25 ]. Table 1 shows the ingredients of the basal diet.…”

Mitigating effect of single or combined administration of nanoparticles of zinc oxide, chromium oxide, and selenium on genotoxicity and metabolic insult in fructose/streptozotocin diabetic rat model

“…It includes the formation and control of particles at “nanoscale” having novel and improved physicochemical properties. Recent study has shown that mineral nanoparticles have greater bioavailability due to their new characteristics, such as greater specific surface area, high catalytic efficiency, higher surface activity, and stronger adsorbing ability, as well as it may be readily carried up by the gastrointestinal tract and used in the animal system and reached to deeper tissues by high efficient than the larger-sized particles (Tag-ElDin 2019 ).…”