Effects of endosulfan on the blood and organ chemistry of freshwater fish, Barbus conchonius hamilton

Gill, Tejendra S.; Pande, Jaishree; Tewari, H. B.

doi:10.1016/0147-6513(91)90010-m

Cited by 46 publications

(25 citation statements)

References 28 publications

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“…Other pesticides, such as endosulfan, have demonstrated their capacity to induce lipid catabolism in fish. Gill et al 35) observed that a depletion in the total lipid content in the muscle of Barbus conchonius exposed to endosulfan was correlated with hypercholesterolemia and fatty acids.…”

Section: Discussionmentioning

confidence: 99%

European eel (<i>Anguilla anguilla</i>) plasma biochemistry alerts about propanil stress

Sancho

Andreau

Villarroel

et al. 2017

Journal of Pesticide Science

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Propanil stress response in the eel (Anguilla anguilla) was examined. Eels were exposed to 3.16 mg/L for 72 hr and allowed to recover for 96 hr. Plasma levels of cortisol, lactate dehydrogenase (LDH), alkaline phosphatase (AP), aspartate aminotransferase (AST), cholesterol, triglycerides, glucose, ammonium, lactate, albumin, and total proteins as well as electrolytes (chloride, sodium, potassium, calcium and phosphorus) were determined. As a consequence of exposure, cortisol, AP, AST, and LDH increased. A hyperglycemic condition, together with hyperlactemia, hypoalbuminemia, hypoproteinemia, hypercholesterolemia and hypertriglycemia was registered. Ammonium increased during exposure concomitantly to hyponatremia, hypochloremia, hypocalcemia, hypophosphatemia, and hypokatremia. During recovery, chloride, sodium, potassium, ammonium, albumin and LDH normalized. At the end of the experiment, fish still exhibited hyperglycemia and hyperlactemia. Hypercalcemia was observed. Cholesterol, triglycerides, AP, and AST did not recuperate. These findings are important for assessing potential risks for areas where fish are grown near intensive herbicide use (i.e., paddy fields).

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Section: Discussionmentioning

confidence: 99%

European eel (<i>Anguilla anguilla</i>) plasma biochemistry alerts about propanil stress

Sancho

Andreau

Villarroel

et al. 2017

Journal of Pesticide Science

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“…Nilai LC 50 insektisida endosulfan terhadap ikan mas (Cyprinus carpio) pada setiap waktu pemaparan (Sulaksono, 2001). Selain sangat toksik terhadap ikan dan organisme akuatik lainnya, insektisida endosulfan juga cukup persisten dan bersifat lipofilik (= suka akan lemak) atau hidropobik (= tidak suka air) dengan nilai log K OW = 4,7 (Greve & Wit, 1979;Gill et al, 1991) sehingga mudah terikat dalam lemak.…”

Section: (Imam Taufik)unclassified

TOKSISITAS SERTA POTENSI BIOAKUMULASI DAN BIOELIMINASI INSEKTISIDA ENDOSULFAN PADA IKAN MAS ( Cyprinus carpio )

Taufik¹,

Setiadi²

2012

Jurnal Riset Akuakultur

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ABSTRAKPenggunaan insektisida endosulfan dalam bidang pertanian berpotensi untuk mencemari sumberdaya dan lingkungan perikanan. Penelitian bertujuan untuk mengetahui toksisitas serta potensi bioakumulasi dan bioeliminasi insektisida endosulfan pada ikan mas. Hewan uji adalah ikan mas berukuran panjang total 3,65 ± 0,247 cm dengan bobot badan 0,81±0,098 g/ekor, bahan uji berupa formulasi insektisida dengan bahan aktif endosulfan 350 g/L. Dilakukan uji toksisitas letal (LC 50 ) dengan metode bioassay untuk waktu pemaparan 24, 48, 72, dan 96 jam; uji bioakumulasi dengan cara memaparkan ikan mas dalam larutan endosulfan pada konsentrasi 0%,10%, 30%, dan 50% dari nilai LC 50 -96 jam; uji bioeliminasi untuk waktu pemaparan dalam air bersih selama 5, 10, dan 15 hari. Analisis konsentrasi endosulfan dalam air dan ikan dilakukan di laboratorium dengan menggunakan gas kromatografi (GC). Hasil menunjukkan bahwa: insektisida endosulfan bersifat sangat toksik terhadap ikan mas dengan nilai LC 50 -96 jam sebesar 2,42 (2,20-2,65) µg/L; bioakumulasi meningkat dengan bertambahnya konsentrasi dan waktu pemaparan hingga mencapai steady state; semakin tinggi konsentrasi endosulfan dalam air maka nilai biokonsentrasi faktor (BCF) akan semakin rendah dan nilai bioeliminasi endosulfan dalam tubuh ikan mas sebesar 0,24% per jam.

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“…A decrease in serum total proteins and albumin, observed in quails following endosulfan feeding has also been reported in fish (Gill et al, 1991). Serum protein synthesis mainly takes place in the liver and is impaired due to many pathological conditions of liver (Latimer et al, 2003).…”

Section: Discussionmentioning

confidence: 92%

Endosulfan (Thiodan® EC 35) induced toxico-pathological effects in male Japanese quails (Coturnix japonica)

Qamar¹,

Khan²,

Khan

et al. 2012

J. Natn. Sci. Foundation Sri Lanka

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Abstract:The objective of the present study was to determine the toxico-pathological effects of endosulfan in Japanese quails. Male Japanese quails (n=120) of 4 weeks of age were administered endosulfan in feed at 0 (control), 5, 25, 50, 100, and 500 mg/kg feed, respectively for 90 consecutive days. The quails of the 5 mg/kg group did not show clinical signs and had significantly lower values of feed intake, testes relative weight and leukocyte number than those of the control group. The quails of the 25 and 50 mg/kg groups had mild depression while those of the 100 and 500 mg/kg groups showed nervous excitation following ingestion of endosulfan. There was a dose related delay in onset of crowing, appearance of foamy material in the droppings and mounting upon the pen mates. The feed intake, body weight, erythrocyte and leukocyte counts, haematocrit values, and serum total proteins of endosulfan fed quails were significantly (p < 0.05) lower than that of the control group. Serum testosterone levels did not change significantly in all the treatment groups. The liver of endosulfan fed birds exhibited fatty change of hepatocytes and necrotic foci in parenchyma. Testes of the endosulfan fed quails had lower weight, volume and diameter of seminiferous tubules compared with control birds. Degenerated spermatids and multinucleated cells were present in the germinal epithelium. Severity of haematological, biochemical and pathological alterations in quails increased with the increase in dietary endosulfan levels. In conclusion, endosulfan in Japanese quails had toxic effects upon liver, nervous, haemopoietic and reproductive system. Moreover, feed intake and body weight also decreased significantly suggesting general toxicity of endosulfan.

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Effects of endosulfan on the blood and organ chemistry of freshwater fish, Barbus conchonius hamilton

Cited by 46 publications

References 28 publications

European eel (<i>Anguilla anguilla</i>) plasma biochemistry alerts about propanil stress

European eel (<i>Anguilla anguilla</i>) plasma biochemistry alerts about propanil stress

TOKSISITAS SERTA POTENSI BIOAKUMULASI DAN BIOELIMINASI INSEKTISIDA ENDOSULFAN PADA IKAN MAS ( Cyprinus carpio )

Endosulfan (Thiodan® EC 35) induced toxico-pathological effects in male Japanese quails (Coturnix japonica)

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