Effects of experimental Haemonchus contortus infection on red blood cells and white blood cells of growing goats

Howlader, M. M. R.; Capitan, Severino S.; Eduardo, Salcedo L.; Roxas, Ninfa P.

doi:10.5713/ajas.1997.679

Cited by 6 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This was similar to findings reported in previous studies, i.e. decreases in RBC (Howlader et al 1997;Qamar & Maqbool 2012), PCV (Al-Quaisy et al 1987), PCV and haemoglobin (Pralomkarn et al 1997;Al-jebory & Al-Khayat 2012), RBC and haemoglobin (Yacob et al 2008), PCV and MCV (Bolormaa et al 2010), PCV, RBC, haemoglobin, MCV and MCH (Ameen et al 2006) (Fakae et al 1999). Reduction in erythrocyte counts and PCV values were reported to be highly correlated with Haemonchus burdens in sheep (Le Jambre 1995), therefore PCV may be used as an essential parameter, besides FEC, to describe resistance against nematode parasites in sheep (Amarante et al 2004).…”

Section: Discussionsupporting

confidence: 93%

“…A previous study reported that there was no significant influence on total WBC counts in growing goats throughout their study following single challenges with H. contortus from 5,000 to a maximum level of 10,000 infective larvae (Howlader et al 1997). However, total leukocyte counts were reported relatively high in infected goats and sheep compared to control groups although no significant differences were observed (Qamar & Maqbool 2012).…”

Section: Leukocytesmentioning

confidence: 84%

“…Previous studies reported decreased RBC (Howlader et al 1997 (Fakae et al 1999). Reduction in erythrocyte counts and PCV values were reported to be highly correlated with Haemonchus burdens in sheep (Le Jambre 1995), therefore PCV may be used as an essential parameter, besides FEC, to describe resistance against nematode parasites in sheep (Amarante et al 2004).…”

Section: Erythrocytesmentioning

confidence: 93%

See 2 more Smart Citations

Development of immunity in boer goats naturally infected with the nematode haemonchus contortus

Abdullah¹

View full text Add to dashboard Cite

Haemonchus contortus (H. contortus) is a major gastrointestinal nematode that adversely affects goat production in tropical and subtropical countries leading to high economic losses due to lower growth rates, markedly reduced reproductive performance and mortality. Farmers can use different strategies including anthelmintic treatments, grazing management, vaccination, improved nutrition and selection of resistant animals in order to control or prevent their animals from infection by this nematode. This study was conducted to determine and describe the development of immunity in Boer goats kids based on their faecal egg count (FEC) and selected blood parameters in relation to specific antibody production against this nematode. Understanding the development of immunity could Many colleagues and organisations (listed below) have contributed to the success of this study, without their assistance this study will not be possible. My sincere appreciation goes to: • The Malaysia government through the Public Services Department of Malaysia for providing me the scholarship to further my study for a higher research degree. • Department of Veterinary Services, Malaysia for allowing me to go on study leave to undertake this degree.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Leukocytesmentioning

confidence: 84%

Section: Erythrocytesmentioning

confidence: 93%

See 1 more Smart Citation

Development of immunity in boer goats naturally infected with the nematode haemonchus contortus

Abdullah¹

View full text Add to dashboard Cite

show abstract

“…A goat kid that has been shown to be free from internal parasites was inoculated orally with a dose of 10, 000 L 3 in 10 ml physiological saline solution as recommended by Jaheed et al [9] and Howlader et al [19] and kept as a donor animal. The donor animal was subsequently used as a source for monospecific L 3 to cause infection in the experimental animals.…”

Section: Genesis Of the Dose Of Infective Larva Of H Contortus Parasmentioning

confidence: 99%

Therapeutic Effect of Balanites Aegyptiaca Fruit’s Ethanol Extract in Egyptian Baladi Goats Experimentally Infected with Haemonchus Contortus: Blood Serum Biochemical, Oxidative Stress Markers and Pathological Studies

et al. 2020

View full text Add to dashboard Cite

the native breed of goats that is located in the Nile Delta and along the Nile Valley is known as Baladi goats. Amongst other breeds of goats, the Baladi goats have a great economic value [1] and play an essential role in the economy of small, marginal farmers and landless labourers in Egypt [2]. T HE THERAPEUTIC effect of Balanites aegyptiaca fruit's ethanolic extract (BAF-EE) in goats experimentally infected with Haemonchus contortus (H. contortus) was evaluated. Serum biochemical parameters, tissue oxidative stress status and pathological changes were investigated. Twelve goats were divided into 4 equal groups, G1 (infected-untreated), G2 (infected-BAF-EE treated), G3 (infected-albendazole treated) and G4 (uninfected-BAF-EE treated). Infection was conducted at 0-time, whereas treatment with BAF-EE and albendazole was given in the 5 th week post infection (PI). Blood samples were drawn on 0-time, 3 rd week PI and then biweekly till the 9 th week for serum biochemical analyses. At the end of experiment, all animals were slaughtered to estimate oxidative stress markers and histopathological alterations in the abomasal and hepatic tissues. Serum biochemistry of infected animals showed significant depression of total serum proteins, albumin, albumin/ globulin ratio, total antioxidant capacity and calcium levels. The activity of AST, ALT and γGT and the cholesterol, urea and creatinine levels were significantly elevated in the serum of infected animals. Glutathione peroxidase values decreased significantly in tissue homogenate of G1 and G3 goats than those in G2 and G4 goats. Malondialdehyde followed a reverse course. Abomasa of infected animals in G1 revealed inflammation, necrosis, petechial hemorrhages and cellular infiltration. Liver showed bile duct hyperplasia, degeneration of hepatocytes and cell infiltration. Intensity of alterations were lower in infected-treated animals. In conclusion, BAF-EE has hepatoprotective effect and can improve serum biochemical alterations and oxidative stress status in goats infected with H. contortus, justifying its use as a safe natural anthelmintic agent.

show abstract

“…1,4,11,13 Additional blood is lost into the gastric lumen because of mucosal irritation, resulting in clinical anemia. Adult worms are 2-3 cm long and can easily be observed at autopsy.…”

Section: Introductionmentioning

confidence: 99%

Pathology of Haemonchus contortus in New World camelids in the southeastern United States

et al. 2016

View full text Add to dashboard Cite

Abstract. Most small ruminant farms in tropical climates are plagued by Haemonchus contortus, a hematophagous, abomasal parasite. Heavy burdens of this parasite can cause anemia, hypoproteinemia, weight loss, and mortality in susceptible animals. Haemonchus contortus is becoming a major health concern in New World camelids as well, namely llamas (Llama glama) and alpacas (Vicugna pacos), yet little research has been conducted regarding its prevalence or pathology in these species. Herein, we present a retrospective review of llamas and alpacas that were admitted to The University of Georgia Veterinary Teaching Hospital and Athens Diagnostic Laboratory between the years 2002 and 2013. Antemortem fecal egg count (FEC) estimates performed on 30 alpacas were negatively correlated with hematocrit, hemoglobin, and red blood cell count. Total protein was not significantly correlated with FEC. On postmortem examination, 55 of 198 camelids, including 2 from the aforementioned antemortem review, were infected with H. contortus, with llamas (42.6%) having a significantly higher infection rate than alpacas (22.2%). In 15.7% of the total cases, the parasite was the major cause of death. Common gross lesions included peritoneal, thoracic, and pericardial effusions, visceral pallor, subcutaneous edema, and serous atrophy of fat. Histologic lesions included centrilobular hepatic necrosis, hepatic atrophy, lymphoplasmacytic inflammation of the mucosa of the third gastric compartment (C3), extramedullary hematopoiesis in both the liver and spleen, and the presence of nematodes in C3. Our study emphasizes the importance of H. contortus diagnosis and herd monitoring in New World camelids, particularly llamas.

show abstract

Effects of experimental Haemonchus contortus infection on red blood cells and white blood cells of growing goats

Cited by 6 publications

References 0 publications

Development of immunity in boer goats naturally infected with the nematode haemonchus contortus

Development of immunity in boer goats naturally infected with the nematode haemonchus contortus

Therapeutic Effect of Balanites Aegyptiaca Fruit’s Ethanol Extract in Egyptian Baladi Goats Experimentally Infected with Haemonchus Contortus: Blood Serum Biochemical, Oxidative Stress Markers and Pathological Studies

Pathology of Haemonchus contortus in New World camelids in the southeastern United States

Contact Info

Product

Resources

About