Effects of high-temperature heat wave and ozone on hypertensive rats

Liang, Tingting; Niu, Jingping; Zhang, Shuyu; Song, Quanquan; Zhou, Ji Shu

doi:10.1007/s00484-019-01788-w

Cited by 6 publications

(2 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Plasminogen activator inhibitor-1 (PAI-1), which could contain fibrinolysis, was found to increase with the exposure of ozone (51) and thus might result in the formation of thrombi. Further, such changes became more significant when combined with heat (60,61). Ozone was also underlined to elevate the risk of thrombosis through platelet activation (52).…”

Section: Discussionmentioning

confidence: 99%

“…Ozone was also underlined to elevate the risk of thrombosis through platelet activation (52). Besides, it was observed that high-density lipoprotein cholesterol (HDL-C) increased when exposed to ozone only (61) and exposed to both ozone and heat (60). In addition, low-density lipoprotein cholesterol (LDL-C) and total cholesterol decreased under combined exposure to ozone and heat (60).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Adverse short-term effects of ozone on cardiovascular mortalities modified by season and temperature: a time-series study

Gao

et al. 2023

Front. Public Health

View full text Add to dashboard Cite

IntroductionAmbient ozone pollution becomes critical in China. Conclusions on the short-term effects of ozone on cardiovascular mortality have been controversial and limited on cause-specific cardiovascular mortalities and their interactions with season and temperature. This research aimed to investigate the short-term effects of ozone and the modifications of season and temperature on cardiovascular mortality.MethodsCardiovascular death records, air pollutants, and meteorological factors in Shenzhen from 2013 to 2019 were analyzed. Daily 1-h maximum of ozone and daily maximum 8-h moving average of ozone were studied. Generalized additive models (GAMs) were applied to evaluate their associations with cardiovascular mortalities in sex and age groups. Effect modifications were assessed by stratifying season and temperature.ResultsDistributed lag impacts of ozone on total cardiovascular deaths and cumulative effects on mortality due to ischemic heart disease (IHD) were most significant. Population under 65 years old was most susceptible. Majority of significant effects were found in warm season, at high temperature, and at extreme heat. Ozone-associated risks in total deaths caused by hypertensive diseases reduced in warm season, while risks in IHD in males increased at high temperature. Extreme heat enhanced ozone effects on deaths caused by CVDs and IHD in the population under 65 years old.DiscussionThe revealed cardiovascular impacts of ozone below current national standard of air quality suggested improved standards and interventions in China. Higher temperature, particularly extreme heat, rather than warm season, could significantly enhance the adverse effects of ozone on cardiovascular mortality in population under 65 years old.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Adverse short-term effects of ozone on cardiovascular mortalities modified by season and temperature: a time-series study

Gao

et al. 2023

Front. Public Health

View full text Add to dashboard Cite

show abstract

Smog Chamber Study on the Ozone Formation Potential of Acetaldehyde

Zhang

Jia

et al. 2021

Adv. Atmos. Sci.

View full text Add to dashboard Cite

Acetaldehyde is one of the important VOC species of O 3 precursors in the atmospheric environment. The influences of relative humidity (RH) and initial VOC/NO x ratio (R CN ) on the formation of O 3 are studied in smog chamber experiments, and the MCM v3.3.1 mechanism of acetaldehyde is modified based on the experimental results. In low-RH conditions (RH = 11.6%±1.1%), the O 3 concentration at 6 h increases first and then decreases with the increase of R CN , and the R CN at the inflection point of O 3 concentrations is 3.2. In high-RH experiments (RH = 78.8%±1.0%), variation of the O 3 concentration at 6 h with R CN is similar to that in low-RH experiments, but the R CN at the inflection point is 2.8. RH has no significant effect on the O 3 concentrations under low R CN (< 3), whereas it has a negative effect under high R CN (> 3). Compared with the experimental results, original MCM v3.3.1 greatly underestimates the O 3 concentrations. Addition of both the photolysis process of peroxyacetyl nitrate and the photolysis process of HNO 3 on the reactor surface into the original MCM can reduce the difference between the simulated O 3 concentrations and the experimental results at 6 h from 24%−35% and 17%−49% to 6%−26% and 10%−42% under low-and high-RH conditions, respectively. The maximum incremental reactivity (MIR) of acetaldehyde simulated with the modified MCM is 4.0 ppb ppb −1 without considering the effect of other VOCs.

show abstract

Climate Change and Heat Stress

Fiamingo,

Hazari

2024

Reference Module in Biomedical Sciences

View full text Add to dashboard Cite

Effects of high-temperature heat wave and ozone on hypertensive rats

Cited by 6 publications

References 40 publications

Adverse short-term effects of ozone on cardiovascular mortalities modified by season and temperature: a time-series study

Adverse short-term effects of ozone on cardiovascular mortalities modified by season and temperature: a time-series study

Smog Chamber Study on the Ozone Formation Potential of Acetaldehyde

Climate Change and Heat Stress

Contact Info

Product

Resources

About