Effects of intravenous lidocaine and/or esmolol on hemodynamic responses to laryngoscopy and intubation: A double-blind, controlled clinical trial

Effect of Dexmedetomidine and Esmolol in Attenuating the Haemodynamic Responses During Laryngoscopy and Endotracheal Intubation in Elective Upper Abdominal Surgeries

“…Kindler et al reported that esmolol administration before laryngoscopy was sufficient to control PR after intubation, but it did not affect sbp. 16 Similar to the above studies in our study Esmolol was significantly more effective than normal saline in obtunding the surge in PR and blood pressure. Scheinin et al 17 studied that 0.6 μg/kg dexmedetomidine decreased, but not totally suppressed, the haemodynamic response to tracheal intubation in healthy individuals.…”

Attenuation of Haemodynamic Responses Following Endotracheal Intubation: A Comparison Between Magnesium Sulphate and Lidocaine

“…10,11,12,13,14 These methods require administration of additional costly drugs, which not only have no role for induction and maintenance of anaesthesia, but also can cause dangerous complications.…”

SUPPRESSION OF PRESSOR RESPONSE DURING LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION BY ESMOLOL ADMINISTERED IN DOSES OF 1.5 mg/kg, 2.25 mg/kg: A COMPARATIVE CLINICAL STUDY

“…Combination of esmolol and lidocaine attenuated both the heart rate and the blood pressure response to intubation. 13 Bensky et al carried out a study using small doses of Esmolol 0.2 mg/kg and 0.4 mg/kg to find out the dose related effects of bolus esmolol on heart rate and blood pressure following laryngoscopy and intubation. Patients received 0.2 mg/kg or 0.4 mg/kg or placebo.…”