Effects of Lactic Acid Bacterial Fermentation on the Antioxidant and Anti-inflammatory Activity of Brown Algae Eisenia bicyclis Extract

Abstract

This study was conducted to evaluate the effect of lactic acid bacterial fermentation on the antioxidant and antiinflammatory activity of an edible brown alga, Eisenia bicyclis. Lactic acid bacteria were inoculated into and cultivated in E. bicyclis water extract. The antioxidant activity of the extract was assayed before and following fermentation. Antioxidant activity was determined by assaying the levels of radical scavenging activity against 2,2′-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl radical and alkyl radical. The lactic acid bacterial fermentation of E. bicyclis extract resulted in enhanced antioxidant activity. The greatest enhancement of antioxidant activity was seen in the DPPH radical scavenging assay, in which E. bicyclis extract was fermented by Pediococcus pentosaceus MBP-34 strain for 12 h. This fermented extract also exhibited higher inhibitory activity (96.66%) on nitric oxide production compared with other lactic acid bacterial fermented extracts or raw extract (189.60%). In conclusion, fermentation by bacterial strain is an attractive strategy for developing value-added food ingredients.

Antioxidative and Anti-inflammatory Effects of Daehwangmokdanphee-tang

“…(Park et al, 2005;Ahn et al, 2006). 대황목단피탕은 대황(Rhei Rhizoma), 목단피(Moutan Cortex), 망초(Natrii sulfas), 도인 (Persicae Semen), 동과자(Beninecasae Semen)로 구성되어 있으 며 이들 각각의 물질이 항산화 및 염증억제에 효과가 있다는 문헌 (Han et al, 2015;Park, 2020;Kim et al, 2000;Lee et al, 2022;Park & Lee, 2020) incubator(MCO-18AC, panasonic, osaka, Japan) 그 외 기기들은 일반적인 실험실 기기를 사용하였다.…”

Novel Composition of Multifunctional Sunblock from Eisenia bicyclis and Aloe vera Extracts and a Mixed Compound of Titanium Dioxide

“…또한, 천연 성분인 새싹인삼과 차풀 복합추출물, 발효 엉겅퀴 추출 물을 이용한 피부 미백효과에 관한 연구가 진행되었으며 Park et al, 2019), 자외선 손상 피부에 대한 미세조 류 Scenedesmus deserticola JD052 추출물의 효능이 보고되었다 (Baek et al, 2018 (Okada et al, 2004). 이들 성분들은 항균, 항염증, 항고지혈증, 항당뇨, 항산화 및 항염증 등의 다양한 기능성 을 가지고 있다고 보고되었다 (Eom et al, 2013;Han et al, 2015;Jang et al, 2008;Jung et al, 2013;Okada et al, 2004). 대황 은 심해조류의 특성상 육상식물과 비교하여 엽록체가 더욱 발달되 어 있으며, 포피린(porphyrin)의 기능이 강한 비타민 B12 포피린계 로 열과 적외선 및 자외선 차단효과가 있다 (Jeon et al, 2009 (Surjushe et al, 2008 (Cho et al, 2006;Zijffers et al, 2010 (Agin, 2006;Youn, 1997;Yoon et al, 2006 서진영.…”