Our purpose in this study was to examine the detectability of a lung nodule at different maximum luminance settings of a liquid-crystal display (LCD) monitor by utilizing receiver operating characteristic (ROC) analysis. The LCD monitor used in this study was calibrated to the grayscale standard display function with different maximum luminance settings (670, 450, and 170 cd/m(2)). The average area under the ROC curve (AUC) and the standard deviation for all observers at 670, 450, and 170 cd/m(2) were 0.837 +/- 0.076, 0.832 +/- 0.051, and 0.830 +/- 0.078, respectively. There was no statistically significant difference in AUC as a function of the maximum luminance setting of the LCD monitor. Considering the results, setting the maximum luminance of an LCD monitor at a higher level may not provide a significant advantage in the detectability of a lung nodule.