Effects of mobile phone radiofrequency on the structure and function of the normal human hemoglobin

Mousavy, Seyed Jafar; Riazi, Gholamhossein; Kamarei, Mahmood; Aliakbarian, Hadi; Sattarahmady, N.; Sharifizadeh, Ahmad; Safarian, Shahrokh; Ahmad, Faizan; Moosavi‐Movahedi, Ali Akbar

doi:10.1016/j.ijbiomac.2009.01.001

Cited by 52 publications

(30 citation statements)

References 83 publications

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“…Extracting and purifying human Hb was done by wellestablished methods (Mousavy et al, 2009). All other materials and reagents were of analytical grade, and solutions were made using double distilled water.…”

Section: Methodsmentioning

confidence: 99%

“…In these tissues, Hb expresses a non-oxygen-carrying function as an antioxidant and also is a regulator of iron metabolism. This blood carrier made up from two α-chains and two β-chains which contain 141 (15126.1 Da) and 146 (15867.2 Da) amino acids, respectively (Mousavy et al, 2009). The α and β subunits contain seven and eight helices, respectively, which are joined together by non-helical segments (Ding, Han, Liu, Zhang, & Sun, 2010).…”

Section: Ghalandari C and Ali Akbar Sabourymentioning

confidence: 99%

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Probing the biological evaluations of a new designed Pt(II) complex using spectroscopic and theoretical approaches: human hemoglobin as a target

Abazari

Shafaei

Divsalar

et al. 2015

Journal of Biomolecular Structure and Dynamics

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In recent years, using heavy metal compounds such as platinum as anticancer agent is one of the common ways in chemical therapy. In this study, a new anticancer compound of glycine derivatives of Pt(II) complex (amyl-glycine1, 10-phenanthroline Platinum nitrate) was designed, and the biological effects of this novel compound on the alterations in the function and structure of human hemoglobin (Hb) at different temperatures of 25 and 37°C were assessed by applying various spectroscopic (fluorescence and circular dichroism (CD)) and theoretical methods. Fluorescence data indicated the strong ability of Pt(II) complex to quench the intrinsic fluorescence of Hb. The binding constant, number of binding sites, and thermodynamic parameters at two temperatures were calculated, and the results indicated the major possibility of occurring van der Waals force or hydrogen bond interactions in the Pt(II) complex-Hb interaction. For evaluating the alteration of secondary structure of Hb upon interaction with various concentrations of complex, far-UV CD spectra were used and it was observed that in high dose of complex, significant changes were occurred which is indicative of some side effects in overdosing of this complex. On the other hand, the molecular docking results illustrate that are well in agreement in obtaining data with spectroscopy. Above results suggested that using Pt(II) complex as an anticancer agent, model drug in high-dose usage might cause some disordering in structure and function of Hb as well as improve understanding of the side effects of newly designed metal anticancer drugs undergoing.

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Section: Methodsmentioning

confidence: 99%

Section: Ghalandari C and Ali Akbar Sabourymentioning

confidence: 99%

Probing the biological evaluations of a new designed Pt(II) complex using spectroscopic and theoretical approaches: human hemoglobin as a target

Abazari

Shafaei

Divsalar

et al. 2015

Journal of Biomolecular Structure and Dynamics

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“…The frequency of the global system for mobile communication (GSM) which being utilized in the majority of the countries is either 900 or 1800 MHz (pulsed at 217 Hz, band width of 200 kHz). The 900 MHz spectrum has two bands including 890-915 MHz, which is particular for handset as well as 935-960 MHz, which is particular for base station antenna (Mousavy et al, 2009). Currently, specific absorption rate (SAR) is the only method available for determining and evaluating thermal and nonthermal effects of EMFs.…”

Section: Introductionmentioning

confidence: 99%

The toxic effects of mobile phone radiofrequency (940 MHz) on the structure of calf thymus DNA

Hekmat

Saboury

Moosavi-Movahedi

2013

Ecotoxicology and Environmental Safety

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“…Furthermore, the research concluded that decrease of oxygen affinity of Hemoglobin corresponded to the electromagnetic frequencies intensity and time of exposure. 6 Among the Malaysian students in medical school found that 124 subjects were aware of the side effects of mobile phone usage. (78 females and 46 males were aware of the hazards) Out of the 124 subjects who were aware of the side effects, 5% of the males and 10% of the females felt that there is no need to minimize the unwanted effects .…”

mentioning

confidence: 99%

Knowledge regarding harmful effects on cell phone use among higher secondary school students Bharatpur Chitwan, Nepal

Gautam

Shakya

2017

J Chitwan Med Coll

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There is no doubt that the cell phone is a very useful today, cell phones are a major part of society. It eases communication with colleagues, friends and relatives. But every technology that provides such benefits comes with consequences. The effect of cell phones on youth and society is excessive. A descriptive cross-sectional study was used to identify the knowledge regarding harmful effects on cell phone use among higher secondary school students. The study population consisted of 70 higher secondary school students of Saptagandaki Multiple College, Bharatpur10, Chitwan. Non-probability purposive sampling technique was used to select the college and faculty .Whereas, out of 145 students, 70 students were selected respectively by using simple random sampling technique from the lottery method. Data was analyzed by using SPSS and various tests frequency, mean, median, percentage and standard deviation and the findings were presented in tables. Chi-square test as inferential statistics was used to analyze the associations between the independent and dependent variables. The study findings revealed that out of the 70 respondents, 24 (34.3%) respondents were in the age of 17 years and 3 (4.3%) respondents were in age of 15 years. The mean age was 17.31 with standard deviation of 1.04. Similarly regarding the sex 45 (64.3%) were male and 25 (35.7%) were female. Respondents' have good level of knowledge regarding harmful effects of cell phone as it causes addiction on cell phone 90.0% but have average level of knowledge as it causes headache 78.6%, gradual loss of hearing 77.1%, eye strain 70.0%, dizziness 71.4%, skin allergy 71.45%, risk for breast cancer 75.7% and have poor level of knowledge as it causes dry eye 47.1%, warmness around ear 35.7%, decrease fertility rate 22.9%, tiredness if used after lights out. Out of 70 respondents, 53 (75.7%) of respondents answered risk for breast cancer is the harmful effects of cell phone if kept on chest region, and 20 (28.6%) answered chest injury. The level of knowledge regarding harmful effects on cell phone use is statistically not-significant with age (p=0.141), sex (p=0.943), faculty (p=0.632), grade (p=0.490) and previous experience (p=0.311).The study concluded that the some educational intervention need to lunch by institution in order to enhance the awareness among higher secondary school students.

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Effects of mobile phone radiofrequency on the structure and function of the normal human hemoglobin

Cited by 52 publications

References 83 publications

Probing the biological evaluations of a new designed Pt(II) complex using spectroscopic and theoretical approaches: human hemoglobin as a target

Probing the biological evaluations of a new designed Pt(II) complex using spectroscopic and theoretical approaches: human hemoglobin as a target

The toxic effects of mobile phone radiofrequency (940 MHz) on the structure of calf thymus DNA

Knowledge regarding harmful effects on cell phone use among higher secondary school students Bharatpur Chitwan, Nepal

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