2019
DOI: 10.9734/ajb2t/2019/v5i130049
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Effects of Ranitidine (Zantac) Drug on the Hormonal Level, Sperm Head Abnormality and Histo-Architecture of the Testis of Albino Male Mice

Abstract: The purposes of this study are to determine the effect of Zantac (Ranitidine) drug on sexual hormones (Testosterone and Prolactin), sperm head abnormality, and histopathological activity on albino male mice testes. Two doses of the drug were used: 1000 and 2000 mg/kg, in addition to a negative control group. Each group included four mice and the drug administrated orally as (0.1 ml) per day for 14 days, and then the mice were sacrificed on the day 15 for laboratory assessment. The result showed tha… Show more

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