Effects of Surface Hydrophilicity and Microtopography on Early Stages of Soft and Hard Tissue Integration at Non‐Submerged Titanium Implants: An Immunohistochemical Study in Dogs

Abstract

Within the limits of this study, it may be concluded that soft and hard tissue integration was influenced mainly by surface hydrophilicity rather than by microtopography.

Microscopic view of osseointegration and functional mechanisms of implant surfaces

“…It has been shown that the healing procedure can be further improved by additional surface modifications of the implant. For example, bone apposition and soft tissue integration were found to be effectively enhanced when a sand-blasted and acid-etched surface was generated on dental implants [3,4].…”

Ultraviolet irradiation enhanced bioactivity and biological response of mesenchymal stem cells on micro-arc oxidized titanium surfaces

“…A major target of implant surface modification is to accelerate and improve osseointegration. Sandblasted and acid-etched titanium surfaces reportedly accelerated and promoted osseointegration and increased boneimplant contact areas 29,30) . Such improvements were reportedly brought about by an increase in hydrophilicity and a decrease in adsorbed hydrocarbons at the surface.…”

Osseointegration and Bioscience of Implant Surfaces - Current Concepts at Bone-Implant Interface

“…Preliminary in vitro studies indicated the hydrophilic nature of titanium surfaces significantly influences the cell differentiation and growth factor production positively (Rausch-Fan et al, 2008;Zhao et al, 2007). Besides, animal studies also shown that on hydrophilic surfaces osseointegration can be established at an early period (Bornstein et al, 2008;Buser at al., 2004;Schwarz et al, 2007). However, there are also contradictory results from other in vitro studies.…”