Static and dynamic compaction of hydrogenated Ti6Al4V powder were investigated experimentally using a hydraulic universal testing machine and with a magnetic pulse compaction (MPC) machine. Effects of discharge voltage, compaction times, compaction temperature, hydrogen content, and compaction method on relative density and mechanical properties of compacts were analyzed. Increasing discharge voltage is an effective method for growth of relative density. Relative density and hardness reach their maximum values of 93.50% and 59.8 HRA under twice compaction, respectively. A proper content of hydrogen improves compressibility and compactability of compacts prepared by MPC. Compaction temperature has a favorable effect on relative density and hardness. The maximum relative density is 95.53% in a hydrogen content of 0.09% at a compaction temperature of 400 C. Compressibility and compactability of compacts prepared by MPC are apparently higher than those of compacts prepared by static compaction.