Effects of the Dental Caries Preventive Procedure on the White Spot Lesions during Orthodontic Treatment—An Open Label Randomized Controlled Trial

Abstract

(1) Background: The aim of this study was to assess the preventive effect of tooth surface disinfection treatment, in addition to fluoride application, during fixed orthodontic treatment. (2) Methods: An open label randomized control trial for the evaluation of the dental caries preventive procedure was performed for the patients with high caries risk who had been visited at Department of Orthodontics, Tsurumi University Dental Hospital for orthodontics treatment. The follow-up period was six months. White spot lesions (WSLs) were evaluated by quantitative light-induced fluorescence (QLF). Cariogenic bacteria were monitored and evaluated by bacterial culture. In addition, the oral microbiome was evaluated by a next-generation sequence (NGS). (3) Results: By the mixed effect modeling, tooth surface disinfection treatment significantly reduced cariogenic bacteria and all parameters obtained by QLF. (4) Conclusions: Tooth surface disinfection treatment, in addition to PMTC and fluoride application, were effective for dental caries prevention and keeping a healthy microbiome during orthodontic treatment.

Oralbiotica/Oralbiotics: The Impact of Oral Microbiota on Dental Health and Demineralization: A Systematic Review of the Literature

“…At the beginning of the orthodontic treatment, incorrect oral hygiene procedures can raise the risk of caries development [ 42 , 78 , 79 , 81 ]. The first step conducts the cavity formation is the clinical highlights of white spot lesion, the early sign of change in the enamel structure, visible at the clinical exam, and affects from 2 to 96–7% of orthodontic patients [ 44 , 78 , 79 , 81 ]. This incipient lesion is determined by the enamel demineralization and hydroxyapatite’s dissolution by the bacteria’s acidic product in the dental plaque [ 78 ].…”

“…Using elastomeric devices with a fluoride release shows that the proportion of Streptococcus Mutans decreases by about 30%, and this result is stable over time compared with conventional modules. Although fluoride released from the elastomeric device is localized, temporary, and needs continuing application, the results improve the role of prevention [ 44 , 78 , 83 ]. Likewise, Ali et al [ 78 ] studied the prevention of using toothpaste containing fluoride to brush tooth surfaces because fluoride ions can prevent dental caries.…”

“…A difference in caries’ severity was noted comparing pcs with fixed therapy (FT) and pcs with aligner therapy (AT) [ 43 ]. FT results in more carious lesions and greater severity, although less extensive; AT, on the other hand, develops less deep, more extensive, and white-spotted lesions [ 44 ], therefore, using AT produces better expectations of oral health conditions [ 41 ]. A difference in higher plaque index was found between fixed lingual therapy and vestibular therapy.…”

Incidence of Postoperative Pneumonia and Oral Microbiome for Patients with Cancer Operation

“…Microbiome analysis was conducted by Bioconductor on free software R ver 4.03. The package used in this study were microbiome, phyloseq, vegan, ape, knitr and Rtsne [19,20].…”

Effects of Magnesium Oxide Nanoparticles Incorporation on Shear Bond Strength and Antibacterial Activity of an Orthodontic Composite: An In Vitro Study

“…Fixed orthodontic treatment is the most preferred mode of treatment for most types of malocclusions [ 1 ]. The complicated undercut of orthodontic devices makes it more difficult to maintain the cleansing of teeth, which can lead to the inducement of dental plaque accumulation, as well as cause alterations in the qualitative and quantitative profile of microbial flora and consequently increase the risk of white spot lesions (WSLs) and dental caries [ 2 , 3 ]. The data from the literature have pointed out the common occurrence of WSL in the course of fixed orthodontic treatments, with incidence and prevalence rates of 45.8% and 68.4%, respectively [ 4 ].…”