Effects of the Ethanol Extract from Lycii folium Leaves on Obesity and Blood Biochemical Indices in High-fat Diet Induced Obese Rats

Abstract

This study was conducted to investigate the effects of ethanol extract from Lycii folium (L. folium) leaves on obesity index, serum lipids, homocysteine, leptin, ghrelin, and glucose in obese rats. Sprague-Dawley rats were administrated high-fat diets to induce obesity. Then, obese rats were divided into three diet groups: a basal-diet obese group (BO group), high-fat diet obese group (FO group), and high-fat diet plus L. folium extract obese group (FLEO group). Three groups were each fed experimental diet for 8 weeks. There were no significant differences in body weight and FER among the groups. However, obesity index such as Röhrer index, Lee index, and T.M. index of FLEO group was significantly decreased as compared to FO group. While serum triglyceride of BO group was significantly decreased as compared to FO group, there were no significant differences in serum lipids, homocysteine, leptin, ghrelin and glucose between FLEO group and FO group. In conclusion, these results indicated that ethanol extract from L. folium leaves might be beneficial with anti-obese effect by reduction of obesity indices in obese rats.

Anti-Obesity Effect of Red Garlic Composites in Rats Fed a High Fat-Cholesterol Diet

“…홍마늘(출원번호; 10-2010-0036798)은 흑마늘의 진한 흑색 2) R+T: red garlic extract+green tea extract by 87.5:12.5 ratio 3) R+F: red garlic extract+citrus dietary fiber by 87.5:12.5 ratio 4) R+TF: red garlic extract+green tea extract+citrus dietary fiber by 87.5:6.25:6.25 ratio 을 개량하기 위하여 저온에서 반복적인 열처리과정으로 적갈 색을 띄는 마늘로 제조된 것을 일컬으며, 생리활성은 생마늘 과 흑마늘의 중간정도로 평가되고 있다 [25]. 홍마늘 분말의 체 내 지질저하 효과는 고지방 식이에 의한 비만 유도 흰쥐에서 흑마늘 분말과 비슷한 결과를 보였으며 [19], 15 brix의 홍마늘 열수추출물을 3∼7% 첨가급이 시 체지방량 감소 및 체내 지질 배설효과가 있다는 연구가 보고되어 있다 [24].…”

“…본 연구는 항산화 활성 및 체내 지질 개선에 효과가 있는 것으로 보고 [19,24,25] [3][4][5][6] Refer to the Values in a column sharing the same superscript letter are not significantly different at p<0.05.…”