Effects of transpulmonary and vascular pressures on pulmonary blood volume in isolated lung.

Interrelationships of flow, intravascular pressure, and tissue perfusion in the measurement of capillary permeability to sodium in isolated dog lung lobes.

“…For example, pulmonary blood volume (PBV) increases as a function of pulmonary artery pressure (Rosenzweig et al, 1970;Maseri et al, 1972;Vreim and Staub, 1974). This increase in PBV may occur by distention of open perfused channels, by recruitment of additional vessels, or by a combination of both mechanisms.…”

Pulmonary Hemodynamics

“…Similar hysteresis between the pressure/flow curves was demonstrated in dogs and cats early on; at the time, it was attributed to the "stress relaxation" or stress history of the vessel walls during the decreasing flow limb of the pulmonary blood pressure/flow cycle (Fung and Sobin, 1972a;Frank et al, 1959;Beck and Lai-Fook, 1983). This finding was not a universal one because other studies did not demonstrate such hysteresis (Maseri et al, 1972;Rosenzweig et al, 1970). The differences between these studies seem to be as much a result of technique as they are physiology.…”

Functions and Control of the Pulmonary Circulation

“…The distribution of blood flow increases almost linearly from the top to the bottom of the lung (FIGURE [1][2][3][4][5]. This distribution of blood flow has been further divided into three functional zones based upon the interaction between the alveolar (P A ), arterial (P a ), and venous (P v ) pressures.…”

“…The exceptions to the latter are alveolar vessels termed "corner vessels." 3,4 These corner vessels differ from other alveolar capillaries in their ability to resist the effects of high alveolar pressures that cause the closure of most alveolar septal capillaries.…”