Effects of Velopharyngeal Dysfunction on Middle Ear of Repaired Cleft Palate Patients

Silva, Daniela Preto da; Collares, Marcus Vinícius Martins; Costa, Sady Selaimen da

doi:10.1597/09-008.1

Cited by 11 publications

(7 citation statements)

References 46 publications

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“…The effect of palatoplasty on otitis media was investigated directly and indirectly in the previous literatures (da Silva et al, 2010;Kobayashi et al, 2012a). In this study, there was no significant difference in the incidence of OME before and after palatoplasty.…”

Section: Discussionmentioning

confidence: 54%

Surveillance of Otitis Media With Effusion in Thai Children With Cleft Palate

Ungkanont

Boonyabut

Komoltri

et al. 2017

The Cleft Palate Craniofacial Journal

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Section: Discussionmentioning

confidence: 54%

Surveillance of Otitis Media With Effusion in Thai Children With Cleft Palate

Ungkanont

Boonyabut

Komoltri

et al. 2017

The Cleft Palate Craniofacial Journal

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“…However, VPI was only assessed at the time of participation in the study, meaning that in some individuals the speech problems may have resolved on their own or bee n mitigated by therapy earlier in life. Other studies have also failed to find a relationship between velopharyngeal function and middle ear status (da Silva et al, 2010). An alternative possible explanation is structural alteration of the Eustachian tube itself and its associated cartilages, which have been documented in cases of CP (reviewed in Bluestone, 2004).…”

Section: Discussionmentioning

confidence: 99%

Ear Infection in Isolated Cleft Lip: Etiological Implications

Ruegg

Cooper

Leslie

et al. 2017

The Cleft Palate Craniofacial Journal

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Background and Hypothesis Chronic ear infections are a common occurrence in children with orofacial clefts involving the secondary palate. Less is known about the middle ear status of individuals with isolated clefts of the lip, although several studies have reported elevated rates of ear infection in this group. The purpose of this retrospective study was to test the hypothesis that chronic ear infections occur more frequently in isolated cleft lip cases (n=94) compared with controls (n=183). Methods A questionnaire was used to obtain information on history of chronic ear infection. The association between ear infection status (present/absent) and cleft lip status (cleft lip case/control) was tested using both chi-square and logistic regression. Results and Conclusions The reported occurrence of chronic ear infection was significantly greater in cleft lipcases (31%) compared to unaffected controls (11%). After adjusting for age and sex, having a cleft lip increased the odds of being positive for ear infection by a factor greater than three (OR=3.698; 95%CI=1.91–7.14). Within cleft lipcases, there was no difference in the occurrence of ear infection by defect laterality or by the type of clefting present in the family history. Although velopharyngeal insufficiency was present in 18.4% of our cleft lip sample, there was no statistical association between ear infection and abnormal speech patterns. These results may have potential implications both for the clinical management of isolated cleft lip cases and for understanding the etiology of orofacial clefting.

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“…Most of the children demonstrated rhinolalia, which indicated prior velopharyngeal problems and/or post‐operative velar insufficiency, often observed after palatal closure [Witt et al, 1997; Da Silva et al, 2010]. This speech impairment is ongoing and could potentially affect social relationships.…”

Section: Discussionmentioning

confidence: 99%

Developmental outcome in Pierre Robin sequence: A longitudinal and prospective study of a consecutive series of severe phenotypes

Thouvenin¹,

Djadi-Prat²,

Chalouhi³

et al. 2013

American J of Med Genetics Pt A

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Pierre Robin sequence (PRS) is a congenital condition with a heterogeneous and imprecise developmental prognosis. We conducted a longitudinal prospective study analyzing the long-term developmental outcome of a consecutive series of 39 children with PRS who had an a priori good prognosis (isolated PRS or PRS associated with a Stickler syndrome) but severe neonatal disorders (respiratory and feeding difficulties). Psychomotor and cognitive levels, speech, and eating behavior were assessed at 15 months of age and 3 and 6 years of age; 24 of the oldest children were interviewed at age 11 or 12 years. Results were analyzed by diagnosis, extent of respiratory and feeding disorders, and treatment modalities. Cognitive scores were within normal ranges and increased over time, from 90.5 at 15 months of age to 109.1 at 6 years. The 24 oldest children were enrolled in the appropriate junior high school grade at the normal age. For children 15 months of age, language scores were below the average, as were scores for vocabulary at 3 years for half of the patients. At 6 years, children's speech showed persistent rhinolalia, which was mild (47%), moderate (11%), or major (11%). At 15 months of age, 74% of the children had satisfactory eating behavior, and 15% had serious difficulties. At 3 and 6 years, 18% and 6% of the children, respectively, had eating problems. Treatment modalities had no significant effect on long-term outcome. Global developmental quotient scores were lower but not significantly for children with an associated Stickler syndrome than those with isolated PRS. Children with isolated PRS showed good prognosis.

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Effects of Velopharyngeal Dysfunction on Middle Ear of Repaired Cleft Palate Patients

Cited by 11 publications

References 46 publications

Surveillance of Otitis Media With Effusion in Thai Children With Cleft Palate

Surveillance of Otitis Media With Effusion in Thai Children With Cleft Palate

Ear Infection in Isolated Cleft Lip: Etiological Implications

Developmental outcome in Pierre Robin sequence: A longitudinal and prospective study of a consecutive series of severe phenotypes

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