2021
DOI: 10.1002/cl2.1127
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Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low‐ and middle‐income countries: A systematic review

Abstract: Background: Almost two billion people who are deficient in vitamins and minerals are women and children in low-and middle-income countries (LMIC). These deficiencies are worsened during pregnancy due to increased energy and nutritional demands, causing adverse outcomes in mother and child. To reduce micronutrient deficiencies, several strategies have been implemented, including diet diversification, large-scale and targeted fortification, staple crop bio-fortification and micronutrient supplementation.Objectiv… Show more

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Cited by 18 publications
(15 citation statements)
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References 494 publications
(1,612 reference statements)
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“…Vitamin D was also correlated with an increase in caesarean section at delivery, across races (Keats et al, 2021). Such evidence gives an indication that Vitamin D is not reducible to black skin formation.…”
Section: )mentioning
confidence: 76%
“…Vitamin D was also correlated with an increase in caesarean section at delivery, across races (Keats et al, 2021). Such evidence gives an indication that Vitamin D is not reducible to black skin formation.…”
Section: )mentioning
confidence: 76%
“…The conditional cash transfer Bolsa Famíliawhich led to reduction of poverty and reaching sustainable development goals, such as maternal mortalitywas terminated in 2021 after 18 years of existence (69) . Vitamin A supplementation during pregnancy had no impact on maternal and child outcomes in low-and middle-income countries (70) , as well as in the postpartum (6) , which led to the discontinuation of the former Brazilian recommendation of vitamin A megadose (200 000 IU) supplementation in the immediate postpartum period for women living in risk areas (71) . Food security policies and nutrition education strategies targeted to priority groupsespecially during pregnancy and lactationshould be a priority in Brazil in order to improve vitamin A food sources availability and ingestion and reduce the burden of vitamin A deficiency in the country.…”
Section: Discussionmentioning
confidence: 99%
“…Intervention approaches may impact factors that are proximal or distal on the causal pathway for malnutrition (UNICEF, 2020), and may impact one or many different nutritional‐related outcomes. Micronutrient interventions, such as supplementation and fortification, are intended to alter micronutrient intakes directly and there is strong evidence for efficacy of these interventions (Keats et al, 2021; Tam et al, 2020), though translating this to effectiveness at scale is a persistent challenge. On the other hand, multisectoral (or “nutrition‐sensitive”) interventions like agriculture or social protection programs have a complex theory of change.…”
Section: How Can Nutrition‐related Impact Investment Respond To Nutri...mentioning
confidence: 99%