Effects of water chemistry variables on gill binding and acute toxicity of cadmium in rainbow trout (Oncorhynchus mykiss): A biotic ligand model (BLM) approach

Niyogi, Som; Kent, Rebecca; Wood, Chris M.

doi:10.1016/j.cbpc.2008.05.015

Cited by 46 publications

(45 citation statements)

References 28 publications

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“…These binding affinity constants indicate that increasing Ca concentrations in the exposure media result in a decrease in the bioaccumulation of Cd, but to a lesser degree than with Zn. The log K CaBL value is comparable to the value based on Cd accumulation datasets reported by Niyogi et al [37] for rainbow trout (namely 3.9), but well under the value for fathead minnow (5) [38]. For Zn, the value (7.4) is close to the one reported by Vercauteren and Blust [39] for the mussel Mytilus edulis (log K ZnBL value of 7.15).…”

Section: Water Chemistry Influence On CD Bioaccumulationsupporting

confidence: 88%

Modeling the effect of water chemistry on the bioaccumulation of waterborne cadmium in zebra mussels

Bourgeault¹,

Gourlay-Francé²,

Tusseau‐Vuillemin³

2010

Enviro Toxic and Chemistry

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The present study aims at investigating the effects of Zn, Ca, and dissolved organic carbon (DOC) on the waterborne Cd bioaccumulation of a freshwater bivalve (Dreissena polymorpha). Mussels were exposed for 48 h at 3 µg/L of Cd in different media. Their physiological activities were assessed by separately measuring the filtration rate in the same exposure water. Increased Zn (from 3 to 89 µg/L) and Ca (from 37 to 131 mg/L) concentrations in water led to a threefold and sevenfold reduction of Cd bioaccumulation, whereas the effect of DOC varied greatly depending on its concentration. At low DOC concentrations (from 0.2 to 1.1 mg/L), the uptake of Cd increased, whereas at higher concentrations (from 1.1 to 17.1 mg/L), the uptake decreased. The filtration activity was not strongly influenced by either Zn or Ca concentration, whereas it was modified in enriched DOC media in the same manner as Cd uptake. A competitive model was built to predict the waterborne uptake rate constant of Cd (k (u)) as a function of Zn and Ca concentrations in the water. Over the range of DOC concentrations we tested, organic matter was shown to influence Cd bioaccumulation in two ways: by modifying Cd speciation and thus its bioavailability and its interaction with the biological membrane, and by affecting the mussel's physiology and therefore its sensitivity to metal. The present study provides a useful means of adjusting the toxicokinetic constant to the water's physicochemical characteristics and proposes a unifying model that takes into account the different geochemical and biological influences on bioaccumulation.

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Section: Water Chemistry Influence On CD Bioaccumulationsupporting

confidence: 88%

Modeling the effect of water chemistry on the bioaccumulation of waterborne cadmium in zebra mussels

Bourgeault¹,

Gourlay-Francé²,

Tusseau‐Vuillemin³

2010

Enviro Toxic and Chemistry

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“…Because of the hormetic-type effects, the protective effect of calcium on the toxicity of metals seen in other studies [10,[36][37][38][39] was not observed in the present study. The EC50 values of 81.6 nM to 191 nM based on dissolved copper concentrations were found for D. magna after 48-h exposure to copper when calcium concentrations increased from 0.2 mM to 4.0 mM [30].…”

Section: Copper Toxicity-time Relationshipscontrasting

confidence: 82%

Toxicodynamics of copper and cadmium inFolsomia candidaexposed to simulated soil solutions

Ardestani¹,

Gestel²

2013

Enviro Toxic and Chemistry

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To improve our understanding of metal bioavailability to soil-living invertebrates, the effect of porewater composition on the toxicodynamics of copper and cadmium in Folsomia candida (Collembola) was investigated. Assuming that porewater is the main exposure route, F. candida was exposed to simulated soil solutions of different composition. Toxicity of copper was slightly lower in a calcium-only solution than in a multication solution. With increasing copper concentrations from 0.005 mM to 1.37 mM, internal copper concentrations similarly increased in both exposure solutions, suggesting that a single cation nutrient solution is suitable for testing F. candida. In the second experiment, animals were exposed for 7 d to copper and cadmium in simplified soil solutions with different calcium (0.2 mM, 0.8 mM, 3.2 mM, 12.8 mM) and pH (5.0, 6.0, 7.0) levels. The median lethal concentration (LC50) values decreased with time in both the calcium and pH series. A hormetic-type effect was observed for copper in the second test, as well as in the calcium-only solution in the first experiment. Because of stronger hormesis, LC50s for copper were higher at lower calcium concentrations. For cadmium, LC50 values were higher at higher calcium concentrations, suggesting competition of calcium with the free cadmium ion. Toxicity of cadmium increased with decreasing pH, while copper was more toxic at intermediate pH. The results show that a toxicodynamics approach can help to improve the interpretation of metal toxicity to soil invertebrates, taking into account soil solution properties.

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“…The present data showed that Na + /K + -ATPase was the most affected ATPase by both salinity and Cd exposures and the gill was the most influenced tissue. This could be due its localization as the first target -ATPase is present in high concentrations in salt transporting tissues like intestine and gills, where it maintains ionic and electrical gradients necessary for transepithelial salt movements (Lionetto et al, 2000;Niyogi et al, 2008). Euryhaline teleosts are able to osmoregulate across a broad spectrum of salinities.…”

Section: Discussionmentioning

confidence: 99%

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Gönener¹,

Özdemir²

2012

Turk. J. Fish. Aquat. Sci.

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Effects of water chemistry variables on gill binding and acute toxicity of cadmium in rainbow trout (Oncorhynchus mykiss): A biotic ligand model (BLM) approach

Cited by 46 publications

References 28 publications

Modeling the effect of water chemistry on the bioaccumulation of waterborne cadmium in zebra mussels

Modeling the effect of water chemistry on the bioaccumulation of waterborne cadmium in zebra mussels

Toxicodynamics of copper and cadmium inFolsomia candidaexposed to simulated soil solutions

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