Background; Vertical shear fractures of the medial malleolus occur through supination–adduction loading of the talus onto the articular surface of the medial malleolus, Aim and objectives; to assess the radiological and functional outcomes of open reduction and internal fixation with antiglide plate of vertical shear medial malleolus fracture, Subjects and methods; This prospective case series study was carried out at the Orthopedics Departments of Al-Azhar University and Health Insurance Hospitals. The study included 22 patients with antiglide plating of vertical medial malleolus fracture. The duration of the study ranged from 6-12 months, Result; Number of patients with Antiglide plate for medial malleolus Management in the study population was 9 (40.91%). Number of patients with Antiglide plate for medial malleolus & Semitubular Plate of lateral malleolus Management in the study population was 13 (59%), Conclusion; Surgical management of vertical shear of medial malleolus fracture gave excellent anatomical reduction and rigid fixation to restore articular congruity, help to facilitate early mobilization and hence to achieve optimal ankle function. The antiglide plate fixation is readily available and cost significantly less than a precountoured anatomicspecific type of fixation.