Efficacy of cognitive rehabilitation using computer software with individuals living with schizophrenia: A randomized controlled trial in Japan.

Iwata, Kazuhiko; Matsuda, Yasuhiro; Sato, Sayaka; Furukawa, Sunao; Watanabe, Yukako; Hatsuse, Norifumi; Ikebuchi, Emi

doi:10.1037/prj0000232

Cited by 27 publications

(27 citation statements)

References 35 publications

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“…Computer-assisted cognitive remediation (CACR) techniques have been shown to improve various cognitive domains and social cognition in schizophrenia. 62 , 67) Another study comparing short-term outcomes of CACR in adolescents with psychotic disorders or at high risk of psychosis 68) revealed significant differences between baseline and follow-up in executive function and reasoning abilities, with better performances at follow-up only in the CACR group. Prediction of positive response and personalization of treatment individualization of such techniques is must as these are labour intensive approaches.…”

Section: Evidence Base For Cognitive Remediationmentioning

confidence: 99%

Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies

Tripathi

Kar

Shukla

2018

Clin Psychopharmacol Neurosci

179

105

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Cognitive deficits are one of the core symptoms of schizophrenia that evolve during the course of schizophrenia, after being originated even before the onset of illness. Existing pharmacological and biological treatment modalities fall short to meet the needs to improve the cognitive symptoms; hence, various cognitive remediation strategies have been adopted to address these deficits. Research evidences suggest that cognitive remediation measures improve the functioning, limit disability bettering the quality of life. The functional outcomes of cognitive remediation in schizophrenia are resultant of neurobiological changes in specific brain areas. Recent years witnessed significant innovations in cognitive remediation strategies in schizophrenia. This comprehensive review highlights the biological correlates of cognitive deficits in schizophrenia and the remedial measures with evidence base.

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Section: Evidence Base For Cognitive Remediationmentioning

confidence: 99%

Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies

Tripathi

Kar

Shukla

2018

Clin Psychopharmacol Neurosci

179

105

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“…In Group 1, one patient had primary education, 6 had vocational education, 13 had secondary education, and 5 had tertiary education. Most of the patients (14) in Group 2 lived in large cities of over 100,000 inhabitants, two lived in smaller towns (below 100,000 inhabitants), and two were country-dwellers. In Group 1, four patients were inhabitants of large cities, 10 lived in smaller towns, and 11 lived in the countryside.…”

Section: Participantsmentioning

confidence: 99%

“…The therapeutic effect of these methods is based on a stimulation mechanism that leads to the restructuring of neuronal connections [11][12][13][14] by inducing changes in the bioelectric activity of the brain and activating the glutamate receptors NMDA (an excitatory neurotransmitter), AMPA (an ionotropic transmembrane receptor) and BDNF (brain derived neurotrophic factor, a member of the nerve growth factor family of proteins) [15][16][17][18][19][20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Activity of BDNF and MMP-9 in Structural Synaptic Modulation in Patients with Schizophrenia Undergoing Rehabilitation

Maciejewski¹,

Dobrowolska²,

Plech³

2020

Preprint

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The aim of the study was to evaluate the levels of brain derived neurotrophic factor (BDNF) and matrix metalloproteinase-9 (MMP-9) in two groups of schizophrenic patients receiving rehabilitation and to find out whether there existed relationships between the levels of these biomarkers and the severity of psychopathological symptoms, changes in event-related potentials (ERP), and quantitative EEG parameters. The study involved two groups of patients diagnosed with schizophrenia in remission who participated in a 12-week conventional rehabilitation program (Group 1) or Biofeedback training (Group 2). The following parameters were assessed: BDNF levels, MMP-9 levels, ERP, QEEG, and psychopathological symptoms (PANSS). (1) The magnitude of changes in the investigated parameters was similar in both groups. (2) Comparable therapy outcomes were obtained for all the dependent variables except for BDNF, whose levels were higher in the GSR-BF patients. GSR Biofeedback can be used as a new alternative to conventional rehabilitation. BDNF can be used as a target in the evaluation of the effectiveness of various rehabilitation modalities, in contrast to MMP-9, which, despite its role in neuromodulation, cannot be treated as a marker of treatment outcomes.

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“…Research by (Iwata et al, 2017) with the research title "Efficacy of cognitive rehabilitation using computer software with individuals living with schizophrenia: A randomized controlled trial in Japan " is an experimental study with randomly. Sixty-five patients with schizophrenia were randomly divided into training groups (n = 33) or non-training groups (n = 32), and compared executive performance with healthy controls (n = 33).…”

Section: Characteristic Of the Researchmentioning

confidence: 99%

Effectiveness of Social Skills Training (Sst) Based on Computer and Manual for Improving Socialization and Social Function of Scizofrenia Patients: Systematic Review

Kotijah¹,

Munfadlila²

2019

IJNMS

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Background: Schizophrenia is part of a psychotic disorder characterized by a loss of understanding of reality and a loss of insight that can be found in symptoms of severe mental disorders such as hallucinations, delusions, chaotic behavior, and chaotic speech, as well as negative symptoms that cause social damage. Psychosocial interventions such as Social Skills Training (SST) is one of the efforts that can be given to schizophrenic patients with the aim of increasing patient socialization and communication skills so that patients are able to adapt to their environment. Research Objectives: To determine the effectiveness of computer-based and manual-based Social Skills Training (SST) on improving the socialization and social function of schizophrenic patients. Data Sources: Sources of data obtained from Pubmed, Sciencedirect, and Ebsco Inclusion Criteria: 1) research studies using the RCT approach, 2) studies in schizophrenic patients in the adolescent-adult age range (17 years-80 years), 3) studies with social therapy interventions, skills training combined social cognitive therapy therapy treatments, both as independent interventions or in combination with other interventions Appraisal studies and synthesis methods: Appraisal studies use the critical appraisal skills program (CASP), and the synthesis method uses PICO modifications. Results: Social skill training (SST) has a significant influence in overcoming the improvement of socialization and social functions Conclusions and Implications of Results: Social skill training (SST) provides a significant influence in improving socialization and social functions so that it can be applied as an effort to overcome social damage. Keyword: Social Skills Training (SST), Social skill training (SST), Computer and Manual.

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Efficacy of cognitive rehabilitation using computer software with individuals living with schizophrenia: A randomized controlled trial in Japan.

Cited by 27 publications

References 35 publications

Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies

Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies

Activity of BDNF and MMP-9 in Structural Synaptic Modulation in Patients with Schizophrenia Undergoing Rehabilitation

Effectiveness of Social Skills Training (Sst) Based on Computer and Manual for Improving Socialization and Social Function of Scizofrenia Patients: Systematic Review

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