Efficacy of Moringa oleifera Leaf Extracts against Cariogenic Biofilm

Jwa, Su-Kyung

doi:10.3746/pnf.2019.24.3.308

Cited by 19 publications

(21 citation statements)

References 24 publications

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“…In the same analysis, at the end of 14 days of treatment, according to the histological cuts, there was a greater reduction in the inflammatory process in the groups treated with Moringa, compared to the control group, with this reduction being even more pronounced in the Moringa group, 10%, it is suggested. this fact is due to its anti-inflammatory property (Jwa, 2019). It was also observed that in the 14-day treatment there was no complete reepithelialization of the wound and the presence of a tissue crust was also observed.…”

Section: Discussionmentioning

confidence: 85%

Efeito do gel a base de Moringa oleifera lam. como fitoterapia na cicatrização de feridas

Moura¹,

Assunção²,

Silva³

et al. 2020

RSD

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Objetivo: Avaliar os efeitos de cicatrização da Moringa oleifera em ratos Wistar. Metodologia: Folhas da moringa foram coletadas, secas, trituradas, misturadas com solvente hexano e filtrada. Após remoção do solvente e da umidade, combinou concentrado resultante ao gel natrosol, alcançando concentrações de 5% e 10%. Dividiu-se 60 ratos machos em 4 grupos: controle negativo (sem tratamento), controle positivo (tratados com AGE), Moringa 5% (tratados com gel de Moringa a 5%) e Moringa 10% (tratados com gel de Moringa a 10%). Subdividiu-se em três grupos de 5 animais de acordo com período de avaliação (7, 14 e 21 dias). Realizou-se na região cervical uma incisão longitudinal (3,0 cm); na região dorsal foi demarcada e ressectada uma área de 2 cm² com um punch. Resultado: Na análise da resistência cicatricial, após 7 dias, os grupos moringa 5% e 10% mostraram uma regressão significante; após 14 e 21 dias, o grupo Moringa 10% apresentou significância estatística quando comparado aos demais grupos. Na análise microscópica, após 7 dias, fibras colágenas mais evidentes nos grupos Moringa 5% e 10%; após 14 e 21 dias, poucos vasos sanguíneos, reação inflamatória de baixa intensidade e deposição de colágeno mais organizada e intensa no grupo Moringa 10%. Conclusão: A moringa, especialmente na concentração de 10%, mostrou-se benéfica no processo reparativo de feridas cutâneas cirurgicamente induzidas em ratos.

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Section: Discussionmentioning

confidence: 85%

Efeito do gel a base de Moringa oleifera lam. como fitoterapia na cicatrização de feridas

Moura¹,

Assunção²,

Silva³

et al. 2020

RSD

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“…Streptococcus mutans causing dental caries is a matter of debate now. As per the study of Jwa (2019) M. oleifera leaf extracts showed antimicrobial activity against S. mutans and inhibits formation of carcinogenic biofilm by retarding its growth. In that study, M. oleifera leaf extract in distilled water (DW) and ethyl alcohol (EtOH) was tested in susceptibility assays for S .…”

Section: Bio‐efficacy Of M Oleifera For Oral Health Carementioning

confidence: 86%

“…This plant has been found to be specific against S. aureus, and E. coli but has no antifungal activity. Its antibacterial activities are responsible for its ability to alleviate toothache (Agbor & Naidoo, 2015, 2019Elgamily et al, 2016). In addition to the above, root decoction of M. oleifera is also used for treatment of toothache when used as mouth rinse as reported by Naidoo (2016, 2019).…”

Section: Biologically Active Compounds With Special Reference To Mamentioning

confidence: 99%

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Phytoperspective of Moringa oleifera for oral health care: An innovative ethnomedicinal approach

Mohanty

Bhuyan

et al. 2020

Phytotherapy Research

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The present era accentuate the use of alternative medicines as drugs extracted from several plant parts. These herbal medicines otherwise called ethnomedicines are now the source of many imperative drugs in this contemporary world. Furthermore with ever rising oral problems by luxurious lifestyle in this modern society, there is a soaring need for use of potent medicinal plants like horse radish (Moringa oleifera Lam.) against various oral ailments. Therefore, use of herbal medicines in reducing the adverse effects of various conventional allopathic medicines and harmful side effects of conventional antibiotics has emerged as an evolved technique in pharmaceutical science. The present review emphasizes the antipathogenic potentiality of M. oleifera along with their known therapeutic properties through biologically active compounds (phytoconstituents) and ethnomedicinal uses. Various ethno‐pharmacological studies of the plant parts with their nutritional value and multifarious medicinal uses including oral health care are being quoted in present review. This review will foster future research on phytoconstituent analysis, bioefficacy assessment for oral micro flora and ethno‐pharmaceutical importance of M. oleifera in the field of medical science with special reference to dentistry. Consequently, this innovative ethnomedicinal approach for oral health care may supplement the modern medicine through its potent phytoconstituents.

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“…M. oleifera leaf showed medicinal properties that improved human oral health care. MO leaf extract inhibited cariogenic biofilm formation and acted against oral pathogens including Staphylococcus aureus , Streptococcus mutans and Candida albicans [ 55 , 56 , 57 ], whereas CC showed significant results for anti-inflammatory and antimicrobial action on S. aureus [ 44 , 58 ]. This present study revealed that the GI from baseline to week 4 in smoker group III (MO + CC lozenges) significantly decreased, indicating that MO + CC lozenges reduced gum inflammation in smokers.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Anti-Inflammatory Effect of Moringa oleifera Lam. and Cyanthillium cinereum (Less) H. Rob. Lozenges in Volunteer Smokers

Luetragoon

Sranujit

Noysang

et al. 2021

Plants

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Smokers have high plaque accumulation that initiates gingival inflammation and progresses to periodontitis. Thus, oral hygiene to control microbial plaque formation is an effective method of preventing gingivitis. Medicinal plants such as Moringa oleifera Lam. (MO) and Cyanthillium cinereum (Less.) H. Rob. (CC) have an anti-inflammatory effect that might improve oral health in smokers. This study evaluated the effect of MO leaf and CC extracts using MO lozenges and a combination of MO + CC lozenges on oral inflammation and gingivitis in volunteer smokers. Lozenges consisting of MO and CC extracts were developed and studied in vivo. The results showed that lozenges significantly reduced oral inflammation and gingivitis in volunteers. The gingival index (GI) of group III (MO + CC lozenges) significantly decreased, while the percentage decrease of oral inflammation in group II (MO lozenges) was significantly higher than the other groups. The percentage decrease of GI values in group II (MO lozenges) and group III (MO + CC lozenges) were significantly higher than the placebo group I. Our findings indicated that MO and MO + CC lozenges reduced oral inflammation and gingivitis and showed potential to improve oral health in smokers.

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Efficacy of Moringa oleifera Leaf Extracts against Cariogenic Biofilm

Cited by 19 publications

References 24 publications

Efeito do gel a base de Moringa oleifera lam. como fitoterapia na cicatrização de feridas

Efeito do gel a base de Moringa oleifera lam. como fitoterapia na cicatrização de feridas

Phytoperspective of Moringa oleifera for oral health care: An innovative ethnomedicinal approach

Evaluation of Anti-Inflammatory Effect of Moringa oleifera Lam. and Cyanthillium cinereum (Less) H. Rob. Lozenges in Volunteer Smokers

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