No abstract

Moringa oleifera leaves are beneficial for human health. Dental caries is closely related with cariogenic biofilm, which is an oral biofilm containing a high proportion of Streptococcus mutans. The purpose of this study was to investigate the antimicrobial effects of the M. oleifera leaf extracts on S. mutans and formation of cariogenic biofilm. Extract from M. oleifera leaves was derived using distilled water (DW) and ethyl alcohol (EtOH). S. mutans susceptibility assays were performed for each extract. Cariogenic biofilm was formed with or without DW and EtOH extract, and cariogenic biofilm was treated with both extracts. The biofilm was observed by confocal laser microscopy, and the bacteria in the biofilm were counted. Both extracts showed antimicrobial activity against S. mutans and inhibited formation of cariogenic biofilm. The EtOH extracts exhibited anti-biofilm activity. M. oleifera leaves may be potential candidates to prevent dental caries.

Background The aim of the study was to observe the antimicrobial activity of Porphyromonas gingivalis and Treponema denticola as well as the effect on reducing volatile sulfur compounds (VSCs). Materials and methods After P. gingivalis and T. denticola were cultured with or without Streptococcus salivarius K12 and M18, VSCs were measured by Oral Chroma. In order to analyze the mechanism for malodor control, the antimicrobial activity of S. salivarius K12 and M18 against P. gingivalis and T. denticola was assessed. SPSS 21.0 was used for data analysis with the Kruskal–Wallis and Jonckheere–Terpstra tests. Mann–Whitney test was applied for post hoc analysis. Results P. gingivalis and T. denticola VSC levels were reduced by high concentrations of S. salivarius K12 and M18 during coculture. The concentrations were lower than those of single culture (p < .05). An antimicrobial effect was detected on P. gingivalis, and T. denticola by 50% S. salivarius K12 and M18. The spent culture medium and whole bacteria of S. salivarius K12 and M18 reduced the levels of VSCs below the amount in a single culture of P. gingivalis and T. denticola (p < .05). Conclusion S. salivarius K12 and M18 decreased the levels of VSCs originating from P. gingivalis and T. denticola.

No abstract

No abstract