Efficiency and Adherence to the Therapy for Hiv Infection in the Republic of Tajikistan

Rahmanov, Erkin; Tsoy, V.G.; Шарипов, Т М; Bukhoriev, Kobiljon; Prevention, Dushanbe

doi:10.25005/2074-0581-2017-19-1-98-102

2017

DOI: 10.25005/2074-0581-2017-19-1-98-102

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Efficiency and Adherence to the Therapy for Hiv Infection in the Republic of Tajikistan

Erkin Rahmanov¹,

V.G. Tsoy²,

Т М Шарипов³

et al.

Abstract: Таджикский государственный медицинский университет им. абуали ибни Сино, Душанбе, Республика Таджикистан 2 Городская клиническая инфекционная больница, Душанбе, Республика Таджикистан 3 Городской центр по профилактике и борьбе со СпиДом, Душанбе, Республика Таджикистан Цель: комплексная оценка эффективности высокоактивной антиретровирусной терапии (ВААРТ) и приверженность к терапии пациентов, находящихся в III и IV клинических стадиях ВИЧ-инфекции. Материал и методы: исследованию подвергнуто 42 пациента, получ… Show more

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Peculiarities of Diagnostics and Course of Uterine Cervical Cancer Among Hiv-Infected Women

Бехтерева¹,

Yaytsev²,

Akhetov³

et al. 2018

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Objective: To assess the clinical course of uterine cervical cancer (UCC) against the background of HIV infection and its complex diagnosis. Methods: A retrospective analysis carried out to 847 outpatient cards of patients for the period 2016-2017. Of these, 17 were HIV-positive. Two groups were formed: group I – patients with UCC on the background of HIV, group II – patients with UCC without HIV. The mean age was 37.4±0.2 and 52.8±0.3 years, respectively. Stages of UCC in group I: IIB – 6 (35.5%), IIIA – 4 (23.5%), IIIB – 6 (35.5%), IVB – 1 (5.5%); in the II group: IB – 3 (15%), IIB – 10 (50%), IIIB – 6 (30%), IVB – 1 (5%). Distribution according to the histological structure in group I: squamous nonkeratinized cancer – 11 (68.75%), keratinizing – 1 (6.25%), adenocarcinoma – 4 (25%). In group II: squamous nonkeratinized cancer – 13 (65%), squamous keratinizing – 3 (15%), adenocarcinoma – 4 (2%). The groups were comparable in treatment methods: in both groups, chemoradiation therapy was used according to standard schemes. Results: Indicators in the I group: lethality – 4 (23.5%), stabilization – 5 (23.5%), progression – 8 (53%); in the second group: lethality – 1 (5%), stabilization – 14 (70%), progression – 5 (25%). Conclusion: UCC in the background of HIV infection occurs at an earlier age. The predominance of stage IIB disease and squamous nonkeratinized cancer in both groups was noted. Mortality within the first year, stabilization and progression in the I and II groups were 23.5%, 23.5%, 53% and 5%, 70%, 25%, respectively. Keywords: Human immunodeficiency virus (HIV), uterine cervical cancer, lethality, stabilization, progressing.

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Peculiarities of Diagnostics and Course of Uterine Cervical Cancer Among Hiv-Infected Women

Бехтерева¹,

Yaytsev²,

Akhetov³

et al. 2018

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The Role and Objectives of Primary Health Care Services Due to Gender- And Agerelated Features of Hiv Infection in Tajikistan

Кадырова¹,

KARIMOV²

2019

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Кафедра семейной медицины № 1, Таджикский государственный медицинский университет им. Абуали ибни Сино, Душанбе, республика Таджикистан 2 республиканский центр по профилактике и борьбе со СПиД, Душанбе, республика Таджикистан Цель: предложение мер повышения эффективности противодействия ВИЧ инфекции в связи с её гендерно-возрастными особенностями в Таджикистане. Материал и методы: проведён сравнительный анализ официальных количественных статистических данных по ВИЧ инфекции Министерства здравоохранения и социальной защиты населения Республики Таджикистан, изучены материалы международных конференций по ВИЧ инфекции, публикации ВОЗ и ЮНЭЙДС и др. Результаты: в Таджикистане в 2017 году зарегистрировано 1207 новых случаев ВИЧ (взрослые, дети), среди которых большинство пациентов было в репродуктивном возрасте, представителями ключевых групп населения, трудовыми мигрантами, беременными женщинами. Основным, прогрессирующим путём передачи ВИЧ был половой (66%). Число людей, живущих с ВИЧ (ЛЖВ), на 1 января 2018 составило 7556 человек, большинство из которых было в репродуктивном возрасте и с увеличением доли женщин среди них. Около 70% ЛЖВ получают лечение против ВИЧ-антиретровирусную терапию, которая в 2017 году впервые назначена 1243 пациентам, многим сразу после постановки диагноза ВИЧ. По результатам рутинного мониторинга вирусной нагрузки для оценки эффективности лечения почти у 70% пациентов отмечено подавление ВИЧ. Заключение: в Таджикистане увеличивается регистрация новых случаев ВИЧ, растёт число ЛЖВ и получающих лечение против ВИЧ. В учреждениях первичной медико-санитарной помощи необходимо усилить просвещение по ВИЧ среди населения, улучшить доступность добровольного ВИЧ тестирования для людей с риском заражения, охватить ВИЧ тестированием всех пациентов по клиническим показаниям и всех беременных женщин. Ключевые слова: ВИЧ инфекция; синдром приобретённого иммунодефицита; люди, живущие с ВИЧ; антиретровирусная терапия; тестирование на ВИЧ; первичная медико-санитарная помощь; репродуктивный возраст. Для цитирования: Кадырова ДА, Каримов СС, Абдухамедов НА. Роль и задачи службы первичной медико-санитарной помощи в связи с гендерно-возрастными особенностями распространения ВИЧ инфекции в Таджикистане.

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Introduction of Hiv Services in the Tajikistan's Primary Health Care Institutions: Dushanbe Experience, Current Results, and Prospects for Further Development

SAYBURKHONOV¹,

KARIMOV²,

Кадырова³

et al. 2023

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Objective: To assess the current results of the integration of HIV services into primary health care (PHC) facilities in Tajikistan in the example of Dushanbe Methods: A comparative analysis of the official statistical data on human immunodeficiency virus infection (HIV) of the Ministry of Health and Social Protection of the Population of the Republic of Tajikistan (MHSP RT) was carried out in dynamics. The data of electronic records of people living with HIV (PLHIV) in the system of electronic tracking of HIV cases, including patients receiving integrated HIV services in PHC facilities, were analyzed. The materials of local and foreign scientific medical journals were studied. The method of descriptive statistics was used in the work. Results: In 2021, 922 new cases of HIV were detected in Tajikistan, including 1) people with sexual transmission – 83.7%; 2) labor migrants (LM) and those tested for clinical indications – 49.2%; 3) people over 50 years of age – 12.3%. The share of LM during HIV testing was 3% of the total population tested for HIV in 2021. The number of PLHIV in the country as of December 31, 2021, was 10,077; 8740 of them (86.7%) received antiretroviral therapy (ART), of which 14.2% were above 50 years of age. As of December 31, 2021, 1,155 (11.5% of all PLHIV in the country) received HIV service at the PHC facilities, 21.2% of them were children (<18 years old), and 78.8% – were adults (18+). Among adult patients, 34.7% were from key population groups (KPs); 1146 (99.2%) PLHIV received ART, of which 97.6% showed viral load (VL) suppression. Coverage of PLHIV with ART in the regions of the country varied from 81.8% to 90.1%. Conclusion: According to the research data, the HIV epidemic continues in the country with increasing infection circulation in the general population and “aging” of HIV. So far, the integration of HIV services into PHC facilities of the country was carried out only in the City Health Centers (CHCs) of Dushanbe, where every third adult PLHIV was from KPs. Almost all PLHIV received ART at the CHCs, and VL suppression was observed in most of them. In the CHCs, it is necessary to expand HIV testing at the initiative of health workers. It is recommended to start implementing the integration of HIV services in the CHCs of other large cities of the country. Keywords: HIV infection, people living with HIV, antiretroviral therapy, viral load suppression, integration of HIV services, primary health care.

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Efficiency and Adherence to the Therapy for Hiv Infection in the Republic of Tajikistan

Cited by 3 publications

References 4 publications

Peculiarities of Diagnostics and Course of Uterine Cervical Cancer Among Hiv-Infected Women

Peculiarities of Diagnostics and Course of Uterine Cervical Cancer Among Hiv-Infected Women

The Role and Objectives of Primary Health Care Services Due to Gender- And Agerelated Features of Hiv Infection in Tajikistan

Introduction of Hiv Services in the Tajikistan's Primary Health Care Institutions: Dushanbe Experience, Current Results, and Prospects for Further Development

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