Efficient and One-pot Synthesis of Tetrahydro[b]Pyran Derivatives Catalyzed by Copper Doped Iron Tartarate

Abstract

The multicomponent environment benign synthesis of tetrahydro[b]pyran derivatives has been prepared by using aldehydes, malanonitrile and dimedone. The reaction is catalyzed by metal tartarate i.e. CuFe2(C4H4O6)3.6H2O, the synthesized catalyst was characterized by XRD and TEM analytical techniques which reveal the crystalline nature, size and shape of the catalyst particles. The used metal tartarate for synthesis was water soluble and reusable hence even after frequent use it did not lost its activity. The products of given three component synthesis was obtained in very short period of time and has moderate to excellent yield. The synthesis includes green approach due to solvent free condition and easy work-up.