Efficient reduction of β-lactoglobulin allergenicity in milk using Clostridium tyrobutyricum Z816

Zhao, Qianru; Wang, Yuwei; Zhu, Zhengming; Zhao, Quanyu; Zhu, Liying; Jiang, Ling

doi:10.1016/j.fshw.2022.09.017

Cited by 31 publications

(8 citation statements)

References 41 publications

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“…Regarding with the expansion of anthropogenic activities, e.g., industrial, agricultural and mining happenings, the level of some contaminants such as potentially toxic elements (PTEs) has increased in different sources including environment, water, soil, and food in recent years ( Akhtar et al, 2021 , Assad et al, 2023 ). Environmental pollution ( Li et al, 2020 , Ma et al, 2022 , Tang et al, 2023 , Zhang et al, 2020 , Zhao et al, 2023 , Zhao et al, 2023 ) in soil ( She, Gao, & Shi, 2023 ), air, water resources, food such as meat ( Özlü et al, 2023 ), rice ( Takooree et al, 2023 ), wheat ( Bai et al, 2023 , Han et al, 2023 ) has increased over decades. These pollutants includes microbial ( Ahmad et al, 2023 , Kamal et al, 2023 , Zhao et al, 2023 , Zhao et al, 2023 ), mycotoxins ( Basso et al, 2023 , Tenge et al, 2022 ) and heavy metals ( Zoghi et al, 2022 ) that cause various diseases ( Guo et al, 2023 ).…”

Section: Introductionmentioning

confidence: 99%

“…Environmental pollution ( Li et al, 2020 , Ma et al, 2022 , Tang et al, 2023 , Zhang et al, 2020 , Zhao et al, 2023 , Zhao et al, 2023 ) in soil ( She, Gao, & Shi, 2023 ), air, water resources, food such as meat ( Özlü et al, 2023 ), rice ( Takooree et al, 2023 ), wheat ( Bai et al, 2023 , Han et al, 2023 ) has increased over decades. These pollutants includes microbial ( Ahmad et al, 2023 , Kamal et al, 2023 , Zhao et al, 2023 , Zhao et al, 2023 ), mycotoxins ( Basso et al, 2023 , Tenge et al, 2022 ) and heavy metals ( Zoghi et al, 2022 ) that cause various diseases ( Guo et al, 2023 ). Furthermore, these elements certainly exist in environment because of natural disaster, weathering, and volcanic reactions ( Braune et al, 2015 ).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Concentration of potentially toxic elements in fillet shrimps of Mediterranean Sea: Systematic review, meta-analysis and health risk assessment

Mahmudiono,

Esfandiari,

Zare

et al. 2024

Food Chemistry: X

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Concentration of potentially toxic elements in fillet shrimps of Mediterranean Sea: Systematic review, meta-analysis and health risk assessment

Mahmudiono,

Esfandiari,

Zare

et al. 2024

Food Chemistry: X

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“…These genes contribute to the intricate network governing immune responses, influencing both the initiation and progression of RA. Am J Transl Res 2024; 16(2):654-668…”

Section: Introductionmentioning

confidence: 99%

Synergistic impact of Gui Zhi Shao Yao Zhi Mu Decoction and leflunomide on gut microbiota in rheumatoid arthritis: insights from 16S rDNA sequencing

Sun

2024

Am J Transl Res

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Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease with complex pathogenesis, including alterations in the gut microbiota. Gui Zhi Shao Yao Zhi Mu Decoction (GSZD), a traditional Chinese herbal formula, has shown efficacy in RA treatment, but its impact on intestinal microflora remains unclear. This study aimed to investigate the effects of GSZD combined with leflunomide on the gut microbiota of RA patients. Methods:The study enrolled 48 RA patients who were randomly assigned to either a control group receiving leflunomide or a treatment group receiving GSZD combined with leflunomide for 12 weeks. Gut microbiota composition was analyzed pre-and post-intervention using 16S rDNA sequencing. Changes in microbial diversity, abundance, and metabolic functions were assessed. Results: Post-treatment, both groups exhibited significant alterations in gut microbiota composition. GSZD combined with leflunomide led to an increased Bacteroidetes/Firmicutes ratio and a reduction in Actinobacteria compared to leflunomide alone. This was associated with beneficial shifts in microbial genera and metabolic pathways, suggesting improved gut health and systemic immune modulation. Conclusion: GSZD combined with leflunomide significantly modulates the gut microbiota in RA patients. This study provides insights into the mechanisms underlying the therapeutic effects of GSZD and highlights the potential of integrating traditional Chinese medicine with conventional treatments in managing RA.

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“…Cow milk protein allergy (CMPA) is an IgE‐mediated reaction to milk proteins and may cause a series of allergic reactions (Oliveira et al ., 2021; Fiocchi, 2022; Meyer, 2022). The most known allergenic proteins in milk are α‐lactalbumin (LA), β‐LG and caseins (Jiang et al ., 2021; Zhao et al ., 2023). Several studies suggested that the incidence of milk protein allergy varies from 0.3% to 7.5% (Elagamy, 2016; Zhang et al ., 2021).…”

Section: Introductionmentioning

confidence: 99%

Physicochemical properties, antigenicity and allergenicity of yoghurt fermented by Lactiplantibacillus plantarum AHQ‐14 combined with starter

Song

Zhang

et al. 2023

Int J of Food Sci Tech

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Summary Cow milk proteins is one of the major food allergens, and some probiotics can abate allergenicity to some extent. Lactiplantibacillus plantarum AHQ‐14 isolated from the traditional dairy products in Xinjiang Province, China, has good ability to reduce the allergenicity of β‐lactoglobulin (LG) and good probiotic properties. In the presented study, L. plantarum AHQ‐14 was used to replace half of the commercial yoghurt starter to ferment yoghurt, and the effects of L. plantarum AHQ‐14 fortification on microstructure, textural and rheological attributes of yoghurt were investigated. In addition, milk protein hydrolysis, antigenicity and allergenicity of yoghurts during 28 days of cold storage were detected. The results indicated that AHQ‐14 and YC‐X11 fermentation could enhance the texture and rheological properties of yoghurt by reducing the syneresis (37%) and firmness (14%) and improving the cohesiveness by 50%. In addition, AHQ‐14 and YC‐X11 fermentation can shorten the fermentation time by about 30 min, SDS‐PAGE displayed that AHQ‐14 and YC‐X11 fermentation had stronger hydrolysis of whey protein compared with YC‐X11 yoghurt. Additionally, the fermentation by L. plantarum AHQ‐14 and YC‐X11 could significantly reduce the antigenicity and IgE‐binding ability of skim milk by 82% and 94%, respectively, thus reducing milk‐allergic reactions in patients significantly.

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Efficient reduction of β-lactoglobulin allergenicity in milk using Clostridium tyrobutyricum Z816

Cited by 31 publications

References 41 publications

Concentration of potentially toxic elements in fillet shrimps of Mediterranean Sea: Systematic review, meta-analysis and health risk assessment

Concentration of potentially toxic elements in fillet shrimps of Mediterranean Sea: Systematic review, meta-analysis and health risk assessment

Synergistic impact of Gui Zhi Shao Yao Zhi Mu Decoction and leflunomide on gut microbiota in rheumatoid arthritis: insights from 16S rDNA sequencing

Physicochemical properties, antigenicity and allergenicity of yoghurt fermented by Lactiplantibacillus plantarum AHQ‐14 combined with starter

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