Eficacia de la administracion de suero y vacuna en el tratamiento antirrabico de ovinos infectados experimentalmente

Abstract

rabia aislado del zorro, analizar su comportamiento a la vacunación como tratamiento post-infeccioso y buscar un modelo animal que permita la evaluación de nuevos esquemas de vacunación post-infecciosa destinados al hombre, se llevó a cabo este trabajo en el cual fueron utilizados 47 ovinos.

Susceptibility of sheep to European bat lyssavirus type-1 and -2 infection: A clinical pathogenesis study☆

“…The disease manifests as the furious form in 80% of the animals, however in some animals the clinical signs were reportedly subtle. Virus was recovered in the CNS and the salivary glands, however only 30% of animals produced an antibody response and 50-60% of animals were protected by vaccination (Baltazar and Blancou, 1995).…”

“…The clinical outcome of these studies was similar to that seen in naturally-occurring cases of rabies, with incubation times between 10-40 days and morbidity around 3 days. In some cases, death occurred peracutely with no clinical signs reported (Soria Baltazar et al, 1992;Baltazar and Blancou, 1995). In one experimental study, greater than 70% of the sheep developed rabies following an intra-muscular inoculation of RABV in a dose dependant manner (Hudson et al, 1996).…”