Attention is called to a hitherto largely overlooked manifestation of fibrous dysplasia. Nine previous cases and 2 new cases of intramuscular myxomas in cases of fibrous dysplasia are reviewed. Ten of the 11 cases had multiple intramuscular myxomas, usually on the right side, and all near but distinct from the bony lesions. All were benign. In 5 cases with Albright's syndrome, the multiple myxomas occurred on the same side as the cutaneous pigmentations. Characteristically, the myxomas made their appearance considerably later in life than the fibrous dysplasia. The literature is reviewed, and the probable pathogenic relationship between myxomas and fibrous dysplasia is discussed.