Eine Maul- und Klauenseuche-Infektion beim Menschen

Eissner, G; Ho, Böhm; Jülich, E

doi:10.1055/s-0028-1103702

Cited by 4 publications

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“…This is not surprising as FMD in man is rare. In reported cases of FMD in man (Vetterlein, 1954;Heinig & Neumerkel, 1964;Pilz & Garbe, 1965;Armstrong, Davie & Hedger, 1967;Eissner, Bohm & Julich, 1967;Suhr Rasmussen, 1968) the source of infection was attributed to drinking infected milk, accidental self-inoculation or to handling infected animals while the skin was damaged by cuts, manicure or by dermatitis. It is likely that in some instances the patients would have inhaled virus in reasonable amounts and infection could also be ascribed to this route.…”

Section: Fmd and Man Removal Of Virus From Nosementioning

confidence: 99%

Inhalation, persistence and dispersal of foot-and-mouth disease virus by man

1970

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SUMMARYSampling of human subjects, who had been in contact with animals infected with foot-and-mouth disease (FMD) virus, showed that virus could be recovered from the nose, throat, saliva and from air expelled during coughing, sneezing, talking and breathing. The amounts of virus recovered paralleled those collected with a large-volume sampler and multistage impinger and these findings confirmed that the highest recovery of airborne virus was from infected pigs followed by cattle and sheep. More virus was found in the noses of those examining infected animals than in those operating the samplers, but there was variation between the subjects. In the majority there was a 1x8 log fall in titre by 3-5 hr., but virus persisted in the nose of one subject for 28 hr. Nose blowing or washing the nostrils did not remove virus completely, nor were cloth or industrial masks completely effective in preventing inhalation of virus. It was possible to transmit virus from infected subjects to others on one occasion. No clinical cases of FMD in man resulted from exposure, nor was there any rise in antibody. Use was made of these findings in determining sites of aerosol excretion in animals, and the results are discussed in relation to FMD in man and to the spread of respiratory viruses by the airborne route.

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Section: Fmd and Man Removal Of Virus From Nosementioning

confidence: 99%

Inhalation, persistence and dispersal of foot-and-mouth disease virus by man

1970

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Virus Infections

Sterling¹

2004

Rook's Textbook of Dermatology

104

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Foot-and-Mouth Disease in Man

1967

The Lancet

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PreliminaryCommunications BRNAH 529 tolerance test, was observed in spite of a markedly prolonged hypoglycaemia. COMMENT In all five subjects studied the mean half relaxation time increased after intravenous glucose administration and decreased after intravenous insulin administration. The increase during the glucose-tolerance test was slow and lagged considerably behind the peak of blood glucose concentration, while the decrease during the insulin-tolerance test was fast and coincided with the drop in blood glucose. This difference in the time relation between blood glucose concentration and half relaxation time in the two tests makes a direct effect of blood glucose on the half relaxation time unlikely. There seems more likely to be an indirect effect, mediated perhaps through a carbohydrate-regulating hormone like adrenaline, growth hormone, or cortisol. The absence of a decrease of the half relaxation time after simultaneous administration of insulin and propranolol suggests that the changes of blood glucose influence the half relaxation time by intermediary of the adrenaline system.Whether the changes of the Achilles tendon reflexogram in thyroid disorders and in diabetes mellitus are related to the adrenaline system requires further investigation. SUMMARYIn five normal subjects the Achilles tendon reflex time was prolonged by intravenous glucose and shortened by intravenous insulin administration. The effect of insulin was abolished when it was given after the application of propranolol.

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Eine Maul- und Klauenseuche-Infektion beim Menschen

Cited by 4 publications

References 0 publications

Inhalation, persistence and dispersal of foot-and-mouth disease virus by man

Inhalation, persistence and dispersal of foot-and-mouth disease virus by man

Virus Infections

Foot-and-Mouth Disease in Man

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