The 66‐year‐old woman was diagnosed with “acute myocardial infarction” due to acute triple vessel occlusion based on clinical symptoms, laboratory examination, and coronary angiography (CAG), but her ECG showed ST‐segment depression in leads aVR and aVL, in addition to ST‐segment elevation in a wide range of leads (V1–V9, V3R–V5R, II, III, and aVF). Thus, a perfect explanation with the existing theory is difficult, and only the case is presented here.