Electrochemical detection of ciprofloxacin based on graphene modified glassy carbon electrode

Xie, Aijuan; Chen, Y.; Luo, Shipin; Tao, Yingrui; Jin, Yang; Li, W.-W.

doi:10.1179/1753555715y.0000000011

Cited by 26 publications

(7 citation statements)

References 55 publications

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“…Several analytical techniques have been used for Cip determination including high-performance liquid chromatography (HPLC), , spectrophotometry, capillary electrophoresis, immunoassay, fluorimetry, field-effect transistor (FET) sensor, and electrochemical method. , Among the above, electrochemical technique with its inherent advantages of high sensitivity and selectivity, quick response, facile miniaturization, and low-cost presents significant potential in online and in situ detection. , Cip is an electroactive substance and the piperazine ring in its structure can be electrochemically oxidized. On the basis of this reaction, several electrochemical sensors were reported for Cip determination. − For instance, the Alahyari group developed a simple and rapid electrochemical method for the determination of ciprofloxacin based on a multiwall carbon nanotube film electrode; this sensor could quantitively detect Cip in a concentration range of 40–1000 μM with a detection limit of 6 μM . The Srivastava group reported a Cip sensor with copper zinc ferrite nanoparticle-modified carbon paste electrode, which had a detection limit of 2.58 μM .…”

Section: Introductionmentioning

confidence: 99%

Nanocomposites of Zr(IV)-Based Metal–Organic Frameworks and Reduced Graphene Oxide for Electrochemically Sensing Ciprofloxacin in Water

Fang

Chen

Liu

et al. 2019

ACS Appl. Nano Mater.

164

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Rapid determination of trace antibiotics is critical for environmental monitoring and the ecosystem. In this study, a sensitive and selective electrochemical sensor for ciprofloxacin (Cip) detection by anodic stripping voltammetry of Cu2+ is designed. Zr(IV)-based metal–organic framework (MOF) NH2–UiO-66 and reduced graphene oxide (RGO) composites are used as working electrodes, which have a large surface area with porous structure and high electrical conductivity. Because Cip can form a stable composite with Cu2+ due to the complexation reaction, the anodic stripping voltammetry method is used for Cip determination with Cu deposition on the NH2–UiO-66/RGO-modified electrode. When Cip is present, the oxidization current of Cu2+ decreases significantly due to the formation of Cu2+–Cip complex. The prepared NH2–UiO-66/RGO sensor can detect trace levels of Cip down to 6.67 nM with a sensitivity of 10.86 μA μM–1, and a linear working range from 0.02 to 1 μM, which is superior to other electrochemical Cip sensors reported previously. The sensor also shows high selectivity, reproducibility, and stability in Cip sensing. Meanwhile, the electrochemical sensor is capable to detect Cip in real water samples with satisfactory recoveries. The ultrasensitivity, rapid detection, and easy operation of the reported sensors present significant potentials for real-time analysis and monitoring of trace antibiotic contaminants in water.

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Section: Introductionmentioning

confidence: 99%

Nanocomposites of Zr(IV)-Based Metal–Organic Frameworks and Reduced Graphene Oxide for Electrochemically Sensing Ciprofloxacin in Water

Fang

Chen

Liu

et al. 2019

ACS Appl. Nano Mater.

164

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“…The obtained data demonstrate that the proposed sensor (ErGO-Clay@CPE) had a high electroanalytical sensing capacity for the identification of Cipro. Compared with other reported electroanalytical-based Cipro sensors, the ErGO-Clay@CPE electrode displays comparable DL and dynamic range of linearity [28][29][30][31][32][33][34][35][36] as summarized in Table I. The discussed results demonstrate that the developed electro-analytical detector provides a good platform for Cipro determination.…”

Section: Resultsmentioning

confidence: 83%

Highly Sensitive and Selective Electrochemical Monitoring of Antibiotic Ciprofloxacin Using Electrochemically Exfoliated@reduced Graphene Oxide/Clay Graphite Electrode

Ariouil¹,

Hrioua²,

Chaibi³

et al. 2023

J. Electrochem. Soc.

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This research covers the development of a green, sensitive, selective, and simple electrochemical strategy for the detection of ciprofloxacin (Cipro) in biological fluids, wastewater, and drug samples. Herein the carbon paste electrode was modified using reduced graphene oxide and clay composite based on the electrochemical reduction of GO (ErGO-Clay@CPE). Electrochemical impedance spectroscopy (EIS) and cyclic voltammetry were used for the electro-characterization of ErGO-Clay@CPE, and the results supported that the ErGO-Clay improved the electrode's conductivity and surface area. Moreover, the electrochemical performance was inspected by differential pulse voltammetry (DPV) and chronoamperometry in phosphate buffer (PB, pH=6). The data demonstrated a magnificent sensitivity of ErGO-Clay@CPE regarding Cipro. Under the optimized operating conditions, the electro-analytical response was linearly related to the Cipro concentration in the range of 0.03-2.0-50.0 µM with a lower detection limit (DL = 3 × SDblank / P) and sensitivity of 2.24 nM and 96.28 µA µM-1 cm-2, respectively. Furthermore, the ErGO-Clay@CPE was applied to identify the Cipro in drugs, wastewater, and urine samples, with satisfied recoveries.

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“…The analytical parameters from the first linear range were computed, with the calculated limit of detection being 0.02 µM and sensitivity being 1.71 µA µM −1 cm −2 . The following equation was used for the calculation [ 38 ] 𝐿𝑂𝐷 = 3σ/S …”

Section: Resultsmentioning

confidence: 99%

Fabrication of ZnWO4/Carbon Black Nanocomposites Modified Glassy Carbon Electrode for Enhanced Electrochemical Determination of Ciprofloxacin in Environmental Water Samples

et al. 2023

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The major problem facing humanity in the world right now is the sustainable provision of water and electricity. Therefore, it is essential to advance methods for the long-term elimination or removal of organic contaminants in the biosphere. Ciprofloxacin (CIP) is one of the most harmful pollutants affecting human health through improper industrial usage. In this study, a zinc tungsten oxide (ZnWO4) nanomaterial was prepared with a simple hydrothermal synthesis. The ZnWO4/Carbon black nanocomposites were fabricated for the determination of CIP. The nanocomposites were characterized by field emission scanning electron microscopy, energy dispersion X-ray spectroscopy, X-ray diffraction, X-ray photoelectron spectroscopy, and electrochemical impedance spectroscopy. Electrochemical studies were done using cyclic voltammetry and differential pulse voltammetry methods. Based on the electrode preparation, the electrochemical detection of CIP was carried out, producing exceptional electrocatalytic performance with a limit of detection of 0.02 μM and an excellent sensitivity of (1.71 μA μM−1 cm−2). In addition, the modified electrode displayed great selectivity and acceptable recoveries in an environmental water sample analysis for CIP detection of 97.6% to 99.2%. The technique demonstrated high sensitivity, selectivity, outstanding consistency, and promise for use in ciprofloxacin detection. Ciprofloxacin was discovered using this brand-new voltammetry technique in a water sample analysis.

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Electrochemical detection of ciprofloxacin based on graphene modified glassy carbon electrode

Cited by 26 publications

References 55 publications

Nanocomposites of Zr(IV)-Based Metal–Organic Frameworks and Reduced Graphene Oxide for Electrochemically Sensing Ciprofloxacin in Water

Nanocomposites of Zr(IV)-Based Metal–Organic Frameworks and Reduced Graphene Oxide for Electrochemically Sensing Ciprofloxacin in Water

Highly Sensitive and Selective Electrochemical Monitoring of Antibiotic Ciprofloxacin Using Electrochemically Exfoliated@reduced Graphene Oxide/Clay Graphite Electrode

Fabrication of ZnWO4/Carbon Black Nanocomposites Modified Glassy Carbon Electrode for Enhanced Electrochemical Determination of Ciprofloxacin in Environmental Water Samples

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