Electrochemical detection of DNA hybridization by a zirconia modified diamond electrode

Novel Aspects of Diamond

“…NDs introduced into Caenorhabditis elegans worm did not cause any detectable stress to worms [198]. In mice, intravenous injection of 50 nm NDs led to long-term entrapment in the liver and the lung [195], but no mice showed any abnormal symptoms. Similarly, subcutaneous and intraperitoneal injection of 100 nm NDs in rats led to accumulation of NDs in retention organs over 1 month with no impact on the rats' viability [197].…”

“…Several long-term in vitro [22,194] and in vivo [195][196][197] previous studies demonstrated that NDs are non-cytotoxic, better tolerated by cells than other nanocarbon materials [198]. NDs introduced into Caenorhabditis elegans worm did not cause any detectable stress to worms [198].…”

“…redox of proteins [189,190]) or for biosensing [56,179,[191][192][193][194]. Zirconia has been used to modify diamond for DNA detection by the Foord group [195]. Several reports exist showing the effectiveness of nickel and nickel hydroxide nanoparticles for glucose oxidase sensing [56,196].…”

Electrocatalytic quantifaction of antitubarcular drug ethionamide in sodium lauryl sulfate

“…Zirconium oxide modified glassy carbon electrode have been used for the detection of various bio molecules such as hemoglobin, cytochrome P450 2B6 and DNA etc. [8][9][10]. To the best of our knowledge, no systematic report is available on the zirconia based voltammetric sensor in solubilized system.…”

Electrochemical detection of a pathogenic Escherichia coli specific DNA sequence based on a graphene oxide–chitosan composite decorated with nickel ferrite nanoparticles

“…It could be observed that there is decrease in MB oxidation current with increasing concentrations of complementary DNA used for hybridization which may be due to hindrance of the MB: guanine interaction driven by duplex formation. 46 The peak current vary logarithmically with DNA concentration in the range 10 À16 to 10 À6 M (Fig. 7B), following the equation;…”