Electrochemical sensor for the detection of dopamine using carbon quantum dots/copper oxide nanocomposite modified electrode

Elugoke, Saheed E.; Fayemi, Omolola E.; Adekunle, Abolanle S.; Mamba, Bhekie B.; Nkambule, Thabo T.I.; Ebenso, Eno E.

doi:10.1016/j.flatc.2022.100372

Cited by 66 publications

(25 citation statements)

References 40 publications

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“…It has been reported that the developed biosensor in the study has superior properties such as high selectivity (101.1 μAμM −1 cm −2 ), rapid response (1 min), a wide linear range (1-5 μM), and a low detection limit (0.6 μM) of pesticide [43]. In another study, Elugoke et al [44] fabricated a novel electrochemical biosensor based on a modified electrode with carbon quantum dots and CuO nanocomposite for the detection of dopamine using square wave voltammetry (SWV). The electrochemical results showed that the carbon quantum dots-CuO nanocomposite-based biosensor exhibited a low LOD of 25.4 μM in a wide linear range from 1 to180 μM.…”

Section: Carbon-based Nanobiosensorsmentioning

confidence: 84%

Nanostructures in Biosensors: Development and Applications

Karabulut¹,

Üllen²,

Karakuş³

2022

Biomedical Engineering

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In recent years, there has been significant interest in advanced nanobiosensor technologies with their exceptional properties for real-time monitoring, ultra-sensing, and rapid detection. With relevant experimental data, highly selective and hypersensitive detection of various analytes is possible using biosensors based on nanostructures. In particular, biosensors focus on vital issues such as disease early diagnosis and treatment, risk assessment of quality biomarkers, food-water quality control, and food safety. In the literature, there has been great attention to the preparation and sensing behavior of several nanomaterials-based sensors, such as polymer frameworks, metal-organic frameworks, one-dimensional (1D) nanomaterials, two-dimensional (2D) nanomaterials, and MXenes-based sensors. This chapter gives points to all aspects of fabrication, characterization, mechanisms, and applications of nanostructures-based biosensors. Finally, some smart advanced sensing systems for ultra-sensing nanoplatforms, as well as a comprehensive understanding of the sensor performances, current limitations, and future outlook of next-generation sensing materials, are highlighted.

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Section: Carbon-based Nanobiosensorsmentioning

confidence: 84%

Nanostructures in Biosensors: Development and Applications

Karabulut¹,

Üllen²,

Karakuş³

2022

Biomedical Engineering

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“…However, since the linear trendlines do not pass through the origin, the oxidation and reduction reactions have involved processes other than the diffusion of electrons [ 39 ]. According to Elugoke and co-workers [ 40 ], the occurrence points demonstrated that the charge transfer process is a diffusion-controlled and surface-confined process. The plot of anodic and cathodic peak potentials against the logarithm of scan rate for PAni-modified SPE is depicted in Figure 3 c, whilst the corresponding electrochemical data are provided in Table S3 in the Supplementary Material .…”

Section: Resultsmentioning

confidence: 99%

Impedimetric Polyaniline-Based Aptasensor for Aflatoxin B1 Determination in Agricultural Products

Ong

Phang

et al. 2023

Foods

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An impedimetric aptasensor based on a polyaniline (PAni) support matrix is developed through the surface modification of a screen-printed carbon electrode (SPE) for aflatoxin B1 (AFB1) detection in foodstuffs and feedstuffs for food safety. The PAni is synthesized with the chemical oxidation method and characterized with potentiostat/galvanostat, FTIR, and UV–vis spectroscopy techniques. The stepwise fabrication procedure of the PAni-based aptasensor is characterized by means of cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) methods. The impedimetric aptasensor is optimized using the EIS technique, and its feasibility of detecting AFB1 in real sample matrices is evaluated via a recovery study in spiked foodstuffs and feedstuffs, such as pistachio nuts, cinnamons, cloves, corn, and soybeans, with a good recovery percentage, ranging from 87.9% to 94.7%. The charge transfer resistance (RCT) at the aptasensor interface increases linearly with the AFB1 concentration in the range of 3 × 10−2 nM to 8 × 10−2 nM, with a regression coefficient (R2) value of 0.9991 and detection limit of 0.01 nM. The proposed aptasensor is highly selective towards AFB1 and partially selective to AFB2 and ochratoxin A (OTA) due to their similar structures that differ only at the carbon–carbon double bond located at C8 and C9 and the large molecule size of OTA.

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“…The cumulative effect of this electrostatic attraction, i.e., the π-π interaction, between DA and the graphitic core (in the CQDs) in the modified carbon paste electrode could be responsible for the outstanding performance in the current response at the pH of 7.0. 56 Nevertheless, with further increase of pH, the peak potential gradually shifted to a more negative side, indicating that the protons participated in the oxidation reactions of DA and UA on the modified electrode. 57 The linear equation for DA and UA was E pa (DA) = −0.0464 pH + 0.561 (R 2 = 0.9992) and E pa (UA) = −0.0526 pH + 0.7191 (R 2 = 0.9941).…”

Section: Optimization Experimentsmentioning

confidence: 97%

“…[39][40][41] The high conductivity, catalytic activity and biocompatibility of metal oxide NPs are supportive for electrochemical processes when they are composited with carbon nanomaterials. [42][43][44][45] The use of carbon paste electrodes (CPE) in the electrochemical measurement of organic species ( pharmaceutical and biomolecules) has been reported. 38,46 These electrodes are highly suitable for the detection of biomolecules through redox reactions.…”

Section: Introductionmentioning

confidence: 99%